Wallin L, Boesby S, Madsen T
Scand J Gastroenterol. 1978;13(7):821-6. doi: 10.3109/00365527809182197.
A measuring unit combined with a perfused catheter has been developed for measurement of the pharyngo-oesophageal sphincter pressure. The system is able to register pressure measurements using either intermittent or continuous withdrawal of the catheter, at the same flow rate (0.5 ml/min). Repeated measurements of pharyngo-oesophageal sphincter pressure have been made on eight healthy volunteers. No differences were found in the sphincter pressures measured by the continuous and the intermittent withdrawal techniques (p greater than 0.10); the coefficient of variation was 0.18 for both techniques. The pharyngo-oesophageal sphincter pressure was measured during infusion of 0.1 N HCl (5 ml/min) 5 cm proximally to the gastro-oesophageal sphincter. There was an increase in the pharyngo-oesophageal sphincter pressure after 1 min of infusion (p less than 0.05). Measurements after 5 min and 10 min were no different from the initial value; thus a fall was observed between the first and the fifth minute (p less than 0.05). The observed rise in sphincter pressure may be explained as a response acting to prevent gastro-oesophageal reflux from entering the pharynx.
一种与灌注导管相结合的测量装置已被开发用于测量咽食管括约肌压力。该系统能够以相同流速（0.5毫升/分钟）通过间歇性或连续性回撤导管来记录压力测量值。对8名健康志愿者进行了咽食管括约肌压力的重复测量。通过连续性和间歇性回撤技术测得的括约肌压力未发现差异（p大于0.10）；两种技术的变异系数均为0.18。在距胃食管括约肌近端5厘米处输注0.1N盐酸（5毫升/分钟）期间测量咽食管括约肌压力。输注1分钟后咽食管括约肌压力升高（p小于0.05）。5分钟和10分钟后的测量值与初始值无差异；因此，在第1分钟和第5分钟之间观察到下降（p小于0.05）。观察到的括约肌压力升高可能被解释为一种防止胃食管反流进入咽部的反应。
