Gilbert J R, Evans C E, Haynes R B, Tugwell P
Can Med Assoc J. 1980 Jul 19;123(2):119-22.
The ability of family physicians to predict patients' compliance with a regimen of digoxin therapy was studied by an analytic survey. Compliance was assessed by a pill count at a home visit and measurement of the serum digoxin level in a blood sample obtained at that visit. Of 74 patients 70% were found to be taking more than 80% of their pills and 86% had a therapeutic serum digoxin level. The 10 physicians were unable to predict compliance better than chance, even for the 58 patients they had known for 5 or more years. Physicians should be cautious in predicting compliance, and when they prescribe oral digoxin therapy they should monitor the patient's compliance by means of the serum digoxin levels.
通过一项分析性调查研究了家庭医生预测患者对洋地黄治疗方案依从性的能力。通过家访时清点药片数量以及在该次家访采集的血样中测量血清洋地黄水平来评估依从性。在74名患者中,发现70%的患者服用的药片超过其应服量的80%,86%的患者血清洋地黄水平处于治疗范围。这10名医生无法比随机猜测更准确地预测依从性,即使对于他们认识5年或5年以上的58名患者也是如此。医生在预测依从性时应谨慎,当他们开具口服洋地黄治疗时,应通过血清洋地黄水平监测患者的依从性。