分泌加压素的鼻腔神经母细胞瘤。病例报告。
Nasal neuroblastoma secreting vasopressin. A case report.
作者信息
Singh W, Ramage C, Best P, Angus B
出版信息
Cancer. 1980 Mar 1;45(5):961-6. doi: 10.1002/1097-0142(19800301)45:5<961::aid-cncr2820450521>3.0.co;2-v.
Abstract
A patient with a nasal neuroblastoma was found to have hypertension and severe hyponatraemia. Radiotherapy and cytotoxic chemotherapy were ineffective in reducing the size and vascularity of the neoplasm. Assay of tumor tissue post mortem revealed high levels of arginine vasopressin. The possibility of vasopressin formation to be added to the better known potential hormonal secretory activities of neuroblastomas.
摘要
一名患有鼻神经母细胞瘤的患者被发现患有高血压和严重低钠血症。放射治疗和细胞毒性化疗在减小肿瘤大小和血管化方面无效。死后对肿瘤组织的检测显示精氨酸加压素水平很高。在神经母细胞瘤更知名的潜在激素分泌活动中增加了加压素形成的可能性。
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