Dev Ophthalmol. 1981;2:248-61.
Xenon are photocoagulation, as carried out in the DRS, is attended by an increased risk of serious macular damage secondary to vitreoretinal traction. This risk is of particular importance in eyes with severe fibrous proliferations and/or localized traction retinal detachment. Little evidence was found of such an effect following argon laser photocoagulation, although some, mostly less serious, visual acuity decreases were attributable to this treatment as well. After 4 years of follow-up, the beneficial effect of xenon photocoagulation in reducing the risk of severe visual loss outweighed its harmful effect, even in eyes with severe fibrous proliferations and/or traction retinal detachment. A beneficial effect of approximately equal magnitude was present in the argon group.
氙光凝术（如在糖尿病性视网膜病变研究中所进行的）会因玻璃体视网膜牵拉而导致严重黄斑损伤的风险增加。这种风险在伴有严重纤维增生和/或局限性牵拉性视网膜脱离的眼中尤为重要。尽管氩激光光凝术后也有一些（大多不太严重）视力下降可归因于该治疗，但几乎没有证据表明氩激光光凝会产生这样的影响。经过4年的随访，即使在伴有严重纤维增生和/或牵拉性视网膜脱离的眼中，氙光凝术在降低严重视力丧失风险方面的有益作用也超过了其有害作用。氩激光组也存在大致相同程度的有益作用。
