Hoes M J, Kreutzer E K, Sijben N
J Clin Chem Clin Biochem. 1981 May;19(5):259-64. doi: 10.1515/cclm.1981.19.5.259.
The excretion of xanthurenic acid in urine after oral intake of 5 grams of L-tryptophan was studied and correlated with test and test-person parameters. The xanthurenic acid was determined by a colorimetric method, which gives reliable and reproducible results. Two groups, of 11 healthy volunteers each, participated. The first group started the test at 08.00 hours and the second group at 22.00 hours. Both groups repeated the same test, within one weed of the first test, at 22.00 hours. The xanthurenic acid excretion in the 24-hour urine correlated significantly (p = 0.04) with urine volume, but did not correlated with age, sex, height, body-weight, urine pH and urinary output of creatinine or 17-hydroxysteroids. The intraindividual variability of the test is not significant. The test should be started in the evening and the urine should be collected over 24 hours. The new reference values for the xar thurenic acid excretion under these conditions are 68.8 +/- 19.0 mumols/24 h.
研究了口服5克L-色氨酸后尿中黄尿酸的排泄情况，并将其与测试和测试对象参数相关联。黄尿酸通过比色法测定，该方法可提供可靠且可重复的结果。两组各有11名健康志愿者参与。第一组在08:00开始测试，第二组在22:00开始测试。两组在第一次测试的一周内，于22:00重复相同测试。24小时尿中黄尿酸排泄量与尿量显著相关（p = 0.04），但与年龄、性别、身高、体重、尿pH值以及肌酐或17-羟类固醇的尿量无关。该测试的个体内变异性不显著。测试应在晚上开始，尿液应收集24小时。在这些条件下，黄尿酸排泄的新参考值为68.8 +/- 19.0微摩尔/24小时。
