Tsuneyoshi M, Enjoji M, Iwasaki H, Shinohara N
Acta Pathol Jpn. 1981 May;31(3):439-47. doi: 10.1111/j.1440-1827.1981.tb01387.x.
This clinicopathologic study concerns 14 cases of extraskeletal myxoid chondrosarcoma from among 603 cases of soft tissue sarcomas. The ages of the patients at the time of initial biopsy ranged from 16 to 69 years. The tumors mainly arose in the lower extremities including buttocks (10 cases), and consisted histologically in cords and strands of small acidophilic cells with occasional vacuolated cells in an abundant myxoid matrix composed of chondroitin sulfate. Electron microscopy in four revealed a continuum of cell differentiation of the tumor cells from chondroblastic cell to undifferentiated mesenchymal cell. Morphological studies indicated that the extraskeletal myxoid chondrosarcoma included so-called chordoid sarcoma, as a variant.
本临床病理研究涉及603例软组织肉瘤中的14例骨外黏液样软骨肉瘤。初次活检时患者年龄为16至69岁。肿瘤主要发生于下肢，包括臀部（10例），组织学上由小嗜酸性细胞的条索和束状结构组成，在富含硫酸软骨素的黏液样基质中偶尔可见空泡化细胞。对4例进行的电子显微镜检查显示肿瘤细胞从软骨母细胞到未分化间充质细胞存在连续的细胞分化。形态学研究表明，骨外黏液样软骨肉瘤包括所谓的脊索样肉瘤这一变异型。
