Weiss S W
Cancer. 1976 Jan;37(1):300-6. doi: 10.1002/1097-0142(197601)37:1<300::aid-cncr2820370140>3.0.co;2-#.
A rare, distinctive neoplasm occurring in the soft tissue of the extremities and resembling chordoma has been recently described and variously termed "chordoid sarcoma," "chordoid tumor," and "parachordoma." An example of this tumor occurring in the flank is presented. The tumor lacks the ultrastructural features associated with chordomas. Moreover, the tumor appears to be elaborating an abundant matrix of sulfated acid mucopolysaccharide interspersed with collagen fibers in varying stages of maturation. These features suggest that the tumor is exhibiting chondroid, rather than chordoid, differentiation. Previous reports of extraskeletal myxoid chondrosarcoma bear a striking light microscopic and electron microscopic similarity to the "chordoid sarcoma," suggesting that the latter is a variant of extraskeletal myxoid chondrosarcoma.
最近报道了一种罕见的、独特的肿瘤，发生于四肢软组织，类似脊索瘤，有多种命名，如“脊索样肉瘤”“脊索样肿瘤”和“副脊索瘤”。本文展示了一例发生于侧腹的该肿瘤病例。该肿瘤缺乏与脊索瘤相关的超微结构特征。此外，肿瘤似乎正在形成丰富的硫酸化酸性粘多糖基质，其间散在着不同成熟阶段的胶原纤维。这些特征提示该肿瘤表现为软骨样而非脊索样分化。先前关于骨外黏液样软骨肉瘤的报道在光镜和电镜下与“脊索样肉瘤”有显著相似性，提示后者是骨外黏液样软骨肉瘤的一种变体。
