芬苯达唑、敌敌畏和盐酸左旋咪唑对猪胃肠道线虫的比较疗效

Comparative efficacy of fenbendazole, dichlorvos, and levamisole HCI against gastrointestinal nematodes of pigs.

作者信息

Marti O G, Stewart T B, Hale O M

出版信息

J Parasitol. 1978 Dec;64(6):1028-31.

Abstract

Forty-two weanling pigs raised under similar management conditions were used to compare the effectiveness of fenbendazole, dichlorvos, and levamisole HCl against Oesophagostomum dentatum, O. quadrispinulatum, Ascaris suum, Trichuris suis, Hyostrongylus rubidus, and Strongyloides ransomi. All three drugs were given in the feed. Eleven pigs served as unmedicated controls; 11 pigs received fenbendazole (3 mg/kg) on days 1, 2, and 3; 10 pigs received dichlorvos (17 mg/kg) on day 3; and 10 pigs received levamisole HCl (8 mg/kg) on day 3. Fecal specimens from all 11 pigs were collected before and after anthelmintic treatment and examined for nematode eggs. All pigs were killed on day 7, and residual nematodes were counted. The calculated efficacies against the above species, respectively, were: fenbendazole, 99.9, 100, 92.4, 66.0, 99.9, and 0%; dichlorvos, 99.4, 99.9, 100, 99.9, 99.9, and 86.9%; levamisole HCl, 97.1, 99.7, 97.9, 26.1, 94.4, and 99.9%.

摘要

选用42头在相似管理条件下饲养的断奶仔猪，比较芬苯达唑、敌敌畏和盐酸左旋咪唑对有齿食道口线虫、四刺食道口线虫、猪蛔虫、猪鞭虫、红色猪圆线虫和兰氏类圆线虫的驱虫效果。三种药物均通过饲料给药。11头猪作为未用药对照；11头猪在第1、2、3天接受芬苯达唑（3毫克/千克）；10头猪在第3天接受敌敌畏（17毫克/千克）；10头猪在第3天接受盐酸左旋咪唑（8毫克/千克）。在驱虫治疗前后收集所有11头猪的粪便样本，检查线虫卵。所有猪在第7天宰杀，计数残留线虫。计算得出对上述虫种的驱虫效果分别为：芬苯达唑，99.9%、100%、92.4%、66.0%、99.9%和0%；敌敌畏，99.4%、99.9%、100%、99.9%、99.9%和86.9%；盐酸左旋咪唑，97.1%、99.7%、97.9%、26.1%、94.4%和99.9%。