Bastianello S S
J S Afr Vet Assoc. 1981 Jun;52(2):105-8.
Canine parvovirus (CPV) myocarditis was diagnosed in 11 puppies during 1979. The diagnosis was made at histopathological examination on the basis of 2 characteristic lesions: a subacute to chronic fibrous myocarditis and the presence of large, basophilic intranuclear inclusions in the cardiac myofibres. The puppies varied from 31/2 to 8 weeks of age and all died suddenly without prior symptoms except for 1 pup which developed a severe respiratory dyspnoea 12 h before death. The presence of white bands or streaks of fibrosis on the endocardial or epicardial surfaces of the ventricles was a characteristic gross finding in 65% of cases. In all cases the lungs revealed a pneumonitis noted as hypercellularity and thickening of the alveolar walls. Alveolar macrophages were present within the alveolar lumens. The latter lesion was regarded to be secondary to heart failure. The clinical symptoms and pathological lesions observed are discussed and compared to these noted by various other workers both in South African and in other countries.
1979年，11只幼犬被诊断出患有犬细小病毒（CPV）心肌炎。诊断是在组织病理学检查的基础上做出的，依据两个特征性病变：亚急性至慢性纤维性心肌炎以及心肌纤维中存在大的嗜碱性核内包涵体。这些幼犬年龄从3.5周到8周不等，除了1只幼犬在死亡前12小时出现严重呼吸性呼吸困难外，所有幼犬均无先兆症状突然死亡。在65%的病例中，心室的心内膜或心外膜表面出现白色纤维化带或条纹是一个特征性大体表现。在所有病例中，肺部均显示出肺炎，表现为肺泡壁细胞增多和增厚。肺泡腔内有肺泡巨噬细胞。后一种病变被认为是心力衰竭的继发表现。本文讨论了观察到的临床症状和病理病变，并与南非和其他国家的其他研究人员所记录的情况进行了比较。
