Lenghaus C, Studdert M J, Finnie J W
Aust Vet J. 1980 Oct;56(10):465-8. doi: 10.1111/j.1751-0813.1980.tb02555.x.
Canine myocarditis virus was inoculated into puppies in utero 8 days before parturition. Puppies were clinically normal at birth. One puppy died 23 days after inoculation and a second puppy was comatose before euthanasia on day 27 post inoculation. Both had acute, non-suppurative myocarditis, and parvovirus was isolated from the heart of each pup. Two other puppies remained clinically normal until euthanasia at 87 and 131 days after inoculation. These latter puppies had extensive, focal fibrosis within the myocardium. Despite weekly monitoring, ECG changes were not recorded. The apparent predilection of canine parvovirus for cardiac myocytes is discussed.
在分娩前8天，将犬心肌炎病毒接种到子宫内的幼犬体内。幼犬出生时临床症状正常。一只幼犬在接种后23天死亡，另一只幼犬在接种后第27天安乐死之前处于昏迷状态。两只幼犬均患有急性非化脓性心肌炎，并且从每只幼犬的心脏中分离出细小病毒。另外两只幼犬在接种后87天和131天安乐死之前临床症状一直正常。这些幼犬的心肌内有广泛的局灶性纤维化。尽管每周进行监测，但未记录到心电图变化。文中讨论了犬细小病毒对心肌细胞的明显偏好。
