Intestinal and cardiopulmonary forms of parvovirus infection in a litter of pups.

Parvovirus infection caused signs of gastrointestinal illness in all pups in a litter of 12 and death in 6 of them when 12 to 19 days old. The remaining pups recovered from the gastrointestinal infection, but 5 of the 6 died before they were 9 1/2 weeks old, with signs of cardiopulmonary disease. Necropsy findings were cardiomegaly, myocarditis, pulmonary congestion, and interstitial pneumonia. The only surviving pup also had signs of cardiopulmonary disease but was apparently well at 18 months of age.