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倍他米松与丁酸氯倍他松滴眼液的比较及其对眼压的影响(作者译)

[Comparison of betamethasone and clobetasone butyrate eye drops and their effect on intraocular pressure (author's transl)].

作者信息

Klemen U M, Drobec P

出版信息

Klin Monbl Augenheilkd. 1981 Jul;179(1):33-5. doi: 10.1055/s-2008-1057255.

Abstract

The effect of clobetasone butyrate eye drops on ocular pressure was tested in 15 steroid responders suffering from different types of conjunctivitis and compared with betamethasone eye drops. Elevated intraocular pressure following application of 0.1% betamethasone eye drops decreased significantly within 2 weeks under medication with 0.1% clobetasone butyrate 4 times daily, whereas fellow eyes kept under treatment with betamethasone suffered further increases in IOP. The therapeutic effect and subjective compatibility of the two steroids were found to be approximately equal.

摘要

在15名患有不同类型结膜炎的类固醇反应者中测试了丁酸氯倍他索滴眼液对眼压的影响,并与倍他米松滴眼液进行了比较。应用0.1%倍他米松滴眼液后眼压升高,在每天4次使用0.1%丁酸氯倍他索治疗的2周内显著降低,而用倍他米松治疗的对侧眼眼压进一步升高。发现两种类固醇的治疗效果和主观耐受性大致相同。

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