Hoehn W, Schroeder F H, Reimann J F, Joebsis A C, Hermanek P
Prostate. 1980;1(1):95-104. doi: 10.1002/pros.2990010113.
Transplantation of tissue from a cribriform human prostatic carcinoma resulted in a serially transplantable tumor line in nude mice, PC 82. During 2 1/2 years the tumor has not changed its histological appearance and remained a moderately differentiated adenocarcinoma. The cells contain large amounts of prostatic acid phosphatase. It has a slow rate of growth and regresses after castration and estrogen treatment. This preliminary information suggests that the PC 82 tumor line may be suitable model for hormone-dependent human prostatic cancer.
将人筛状前列腺癌组织移植到裸鼠体内，产生了一种可连续传代移植的肿瘤系，即PC 82。在2年半的时间里，该肿瘤的组织学外观没有改变，仍然是中分化腺癌。细胞中含有大量前列腺酸性磷酸酶。它生长缓慢，去势和雌激素治疗后会消退。这一初步信息表明，PC 82肿瘤系可能是激素依赖性人类前列腺癌的合适模型。
