Adams T D, Yanowitz F G, Fisher A G, Ridges J D, Lovell K, Pryor T A
Circulation. 1981 Nov;64(5):958-65. doi: 10.1161/01.cir.64.5.958.
The purpose of this study was to assess noninvasively the effects of intense aerobic training on cardiac structure and function in a group of healthy, college-age men (25 experimental and 11 control, mean age 22 years). Echocardiographic, electrocardiographic (ECG), and fitness measurements were obtained before and after a 3-month endurance training program and compared with similar measurements obtained in nonexercising subjects. The supervised training program consisted of 50-minute jogging sessions 5 days a week at 85% of maximal heart rate. Compared with the control group, echocardiography after training showed an increase in left ventricular (LV) end-diastolic dimension (p less than 0.05). LV posterobasal wall thickness, septal wall thickness and ejection fraction did not change significantly. ECG measurements revealed a decrease in resting heart rate (p less than 0.05) and an increase in R-wave voltage in leads V5 and V6 (p less than 0.01). The measured maximal oxygen consumption increased by 16% (p less than 0.001). These data indicate that intense aerobic training in college-age men results in a significant increase in resting LV end-diastolic dimension and volume. The increase in maximal stroke volume associated with exercise training may be partially explained by these changes in cardiac dimensions.
本研究的目的是对一组健康的大学适龄男性(25名实验组和11名对照组,平均年龄22岁)进行无创评估,以确定高强度有氧训练对心脏结构和功能的影响。在为期3个月的耐力训练计划前后进行了超声心动图、心电图(ECG)和体能测量,并与未进行运动的受试者的类似测量结果进行比较。有监督的训练计划包括每周5天、每次50分钟的慢跑,速度为最大心率的85%。与对照组相比,训练后的超声心动图显示左心室(LV)舒张末期内径增加(p<0.05)。左心室后基底壁厚度、室间隔厚度和射血分数无显著变化。心电图测量显示静息心率降低(p<0.05),V5和V6导联的R波电压升高(p<0.01)。测得的最大耗氧量增加了16%(p<0.001)。这些数据表明,大学适龄男性进行高强度有氧训练会导致静息左心室舒张末期内径和容积显著增加。与运动训练相关的最大每搏输出量的增加可能部分归因于心脏尺寸的这些变化。