拟杆菌属诱导和抑制多形核中性粒细胞趋化作用
Polymorphonuclear neutrophil chemotaxis induced and inhibited by Bacteroides spp.
作者信息
Adamu S A, Sperry J F
出版信息
Infect Immun. 1981 Sep;33(3):806-10. doi: 10.1128/iai.33.3.806-810.1981.
Abstract
A possible virulence factor for Bacteroides subcutaneous abscesses has been found. The effect of Bacteroides culture filtrate and outer membrane on chemotaxis of rabbit peritoneal polymorphonuclear (PMN) neutrophils was assayed in Boyden chambers and via exocytosis of N-acetyl-beta-glucosaminidase. Both Bacteroides culture filtrate and outer membrane elicited some chemotaxis, as measured in the Boyden chamber; however, they had little effect upon exocytosis in cytochalasin B-treated PMN neutrophils. In the presence of serum complement, they completely abolished PMN neutrophil movement in the Boyden chamber assay, yet they gave a definite positive response for the exocytosis assay in the presence of serum complement or activated complement fragment.
摘要
已发现一种可能导致拟杆菌皮下脓肿的毒力因子。在博伊登小室中并通过N-乙酰-β-葡萄糖胺酶的胞吐作用，测定了拟杆菌培养滤液和外膜对兔腹膜多形核（PMN）中性粒细胞趋化性的影响。如在博伊登小室中所测，拟杆菌培养滤液和外膜均引发了一定程度的趋化性；然而，它们对细胞松弛素B处理的PMN中性粒细胞的胞吐作用影响很小。在血清补体存在的情况下，它们在博伊登小室试验中完全抑制了PMN中性粒细胞的移动，但在血清补体或活化补体片段存在的情况下，它们在胞吐作用试验中给出了明确的阳性反应。
相似文献
1
Polymorphonuclear neutrophil chemotaxis induced and inhibited by Bacteroides spp.拟杆菌属诱导和抑制多形核中性粒细胞趋化作用
Infect Immun. 1981 Sep;33(3):806-10. doi: 10.1128/iai.33.3.806-810.1981.
2
Effect of Bacteroides fragilis cellular components on chemotactic activity of polymorphonuclear leukocytes towards Escherichia coli.脆弱拟杆菌细胞成分对多形核白细胞趋化大肠杆菌活性的影响。
J Med Microbiol. 1987 Sep;24(2):119-24. doi: 10.1099/00222615-24-2-119.
3
Polymorphonuclear leukocyte chemotaxis by mixed anaerobic and aerobic bacteria.
J Med Microbiol. 1984 Oct;18(2):167-72. doi: 10.1099/00222615-18-2-167.
4
Polymorphonuclear neutrophil chemotaxis modulated by Bacteroides fragilis peptidoglycan.脆弱拟杆菌肽聚糖调节多形核中性粒细胞趋化作用。
Infect Immun. 1987 Jul;55(7):1725-7. doi: 10.1128/iai.55.7.1725-1727.1987.
5
A Bacteroides by-product inhibits human polymorphonuclear leukocyte function.
Arch Surg. 1986 Jan;121(1):82-8. doi: 10.1001/archsurg.1986.01400010096012.
6
Succinic acid production by Bacteroides fragilis. A potential bacterial virulence factor.脆弱拟杆菌产生琥珀酸。一种潜在的细菌毒力因子。
Arch Surg. 1987 Jan;122(1):93-8. doi: 10.1001/archsurg.1987.01400130099015.
7
A soluble Bacteroides by-product impairs phagocytic killing of Escherichia coli by neutrophils.一种可溶性拟杆菌副产物会损害中性粒细胞对大肠杆菌的吞噬杀伤作用。
Infect Immun. 1989 Mar;57(3):745-53. doi: 10.1128/iai.57.3.745-753.1989.
8
Chemotaxis or migration inhibition of rabbit peritoneal polymorphonuclear leukocytes caused by chemoattractants at various concentrations.不同浓度趋化因子引起的兔腹膜多形核白细胞的趋化作用或迁移抑制。
Acta Pathol Microbiol Scand B. 1979 Oct;87(5):285-90. doi: 10.1111/j.1699-0463.1979.tb02440.x.
9
The importance of C5 and the role of the alternative complement pathway in leukocyte chemotaxis induced in vivo and in vitro by Bacteroides fragilis lipopolysaccharide.C5的重要性以及替代补体途径在脆弱拟杆菌脂多糖体内外诱导的白细胞趋化作用中的作用。
Acta Pathol Microbiol Scand B. 1978 Apr;86(2):93-100. doi: 10.1111/j.1699-0463.1978.tb00015.x.
10
Rabbit polymorphonuclear leukocyte chemotactic factor generated in vivo by Bacteroides fragilis lipopolysaccharide. II. Antigenic and biologic properties.脆弱拟杆菌脂多糖在体内产生的兔多形核白细胞趋化因子。II. 抗原性和生物学特性。
Acta Pathol Microbiol Scand B. 1978 Aug;86(4):237-45. doi: 10.1111/j.1699-0463.1978.tb00037.x.
引用本文的文献
1
Stimulation of migration of human monocytes by bacterial cell walls and muramyl peptides.细菌细胞壁和胞壁酰肽对人单核细胞迁移的刺激作用。
Infect Immun. 1982 Dec;38(3):817-24. doi: 10.1128/iai.38.3.817-824.1982.
2
The identification and antimicrobial susceptibility of anaerobic bacteria from pneumonic cattle lungs.患肺炎牛肺中厌氧菌的鉴定及药敏试验
Can J Comp Med. 1983 Jul;47(3):270-5.
3
Immunobiological activities of synthetic lipid A analogs and related compounds as compared with those of bacterial lipopolysaccharide, re-glycolipid, lipid A, and muramyl dipeptide.合成类脂A类似物及相关化合物与细菌脂多糖、再糖脂、类脂A和胞壁酰二肽相比的免疫生物学活性。
Infect Immun. 1983 Aug;41(2):758-73. doi: 10.1128/iai.41.2.758-773.1983.
4
Host response to mixed anaerobic infection with Bacteroides melaninogenicus and Fusobacterium necrophorum.宿主对产黑色素拟杆菌和坏死梭杆菌混合厌氧感染的反应。
Infection. 1983 Jan-Feb;11(1):35-40. doi: 10.1007/BF01651356.
5
Polymorphonuclear neutrophil chemotaxis modulated by Bacteroides fragilis peptidoglycan.脆弱拟杆菌肽聚糖调节多形核中性粒细胞趋化作用。
Infect Immun. 1987 Jul;55(7):1725-7. doi: 10.1128/iai.55.7.1725-1727.1987.
6
Recurrent genital tract infections: a result of induced immunosuppression.复发性生殖道感染：诱导性免疫抑制的结果。
Genitourin Med. 1990 Oct;66(5):409. doi: 10.1136/sti.66.5.409-a.
本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Studies on glucosaminidase. 3. Testicular N-acetyl-beta-glucosaminidase and N-acetyl-beta-galactosaminidase.氨基葡萄糖苷酶的研究。3. 睾丸N-乙酰-β-氨基葡萄糖苷酶和N-乙酰-β-半乳糖苷酶。
Biochem J. 1961 Jan;78(1):111-6. doi: 10.1042/bj0780111.
3
Variations of Bacteroides fragilis with in vitro passage: presence of an outer membrane-associated glycan and loss of capsular antigen.脆弱拟杆菌体外传代后的变异：外膜相关聚糖的存在及荚膜抗原的丧失。
J Infect Dis. 1980 Nov;142(5):750-6. doi: 10.1093/infdis/142.5.750.
4
Participation of normal human immunoglobulins M, G, and A in opsonophagocytosis and intracellular killing of Bacteroides fragilis and Bacteroides thetaiotaomicron by human polymorphonuclear leukocytes.正常人免疫球蛋白M、G和A参与人多形核白细胞对脆弱拟杆菌和嗜热栖热放线菌的调理吞噬作用及细胞内杀伤。
Infect Immun. 1980 May;28(2):633-7. doi: 10.1128/iai.28.2.633-637.1980.
5
Opsonization of four Bacteroides species: role of the classical complement pathway and immunoglobulin.四种拟杆菌属细菌的调理作用：经典补体途径和免疫球蛋白的作用
Infect Immun. 1980 Mar;27(3):784-92. doi: 10.1128/iai.27.3.784-792.1980.
6
Intraphagocytic beta-N-acetylglucosaminidase. Properties of the enzyme and its activity on group A streptococcal carbohydrate in comparison with a soil bacillus enzyme.吞噬细胞内β-N-乙酰氨基葡萄糖苷酶。该酶的特性及其对A组链球菌碳水化合物的活性与一种土壤芽孢杆菌酶的比较
J Exp Med. 1968 Apr 1;127(4):833-51. doi: 10.1084/jem.127.4.833.
7
Chemical characteristics of endotoxin from Bacteroides fragilis NCTC 9343.脆弱拟杆菌NCTC 9343内毒素的化学特性
J Gen Microbiol. 1970 Apr;61(1):15-9. doi: 10.1099/00221287-61-1-15.
8
Nutritional features of Bacteroides fragilis subsp. fragilis.脆弱拟杆菌脆弱亚种的营养特征。
Appl Microbiol. 1974 Aug;28(2):251-7. doi: 10.1128/am.28.2.251-257.1974.
9
Leukocyte locomotion and chemotaxis. New methods for evaluation, and demonstration of a cell-derived chemotactic factor.白细胞移动与趋化性。评估及证明一种细胞源性趋化因子的新方法。
J Exp Med. 1973 Feb 1;137(2):387-410. doi: 10.1084/jem.137.2.387.
10
Bactericidal activity of aerobic and anaerobic polymorphonuclear neutrophils.需氧和厌氧多形核中性粒细胞的杀菌活性。
Infect Immun. 1974 Feb;9(2):337-41. doi: 10.1128/iai.9.2.337-341.1974.
Zotero 插件