Wightman R M, Strope E, Plotsky P, Adams R N
Brain Res. 1978 Dec 22;159(1):55-68. doi: 10.1016/0006-8993(78)90109-9.
An in vivo electrochemical system which continuously records the concentration of metabolites of biogenic amines in small animal CSF is described. A small electrode, immersed in lateral ventricle CSF through a guide cannula, measures the amine metabolites by voltammetric oxidation. The detailed results of HVA release following electrical stimulation of the nigrostriatal pathway in rats are presented and compared with previous perfusion data. All the electrochemical results are verified by independent liquid chromatographic (chemical) analysis.
本文描述了一种可连续记录小动物脑脊液中生物胺代谢物浓度的体内电化学系统。一个小电极通过引导套管浸入侧脑室脑脊液中，通过伏安氧化法测量胺代谢物。文中给出了电刺激大鼠黑质纹状体通路后高香草酸释放的详细结果，并与之前的灌注数据进行了比较。所有电化学结果均通过独立的液相色谱（化学）分析进行验证。
