Mathur R P, Prakash I
J Hyg (Lond). 1981 Oct;87(2):179-84. doi: 10.1017/s0022172400069382.
Brodifacoum was evaluated in the laboratory against the two gerbils, Tatera indica and Meriones hurrianae and the house rat, Rattus rattus. The acute oral LD50 for these rodents was found to be 0.10 mg/kg, 0.083 mg/kg and 0.77 mg/kg respectively. Feeding tests with 0.002% and 0.005% brodifacoum produced a 100% mortality after a 3-day feeding period in the gerbils and after a 4-day period in R. rattus. The anticoagulant is toxic at both the concentrations to all three species but is less palatable in comparison to plain baits. Results of this laboratory evaluation indicates that 0.002% brodifacoum-treated bait can be effectively used against T. indica, M. hurrianae and R. rattus.
在实验室中对溴敌隆进行了针对两种沙鼠(印度大沙鼠和印度沙漠大沙鼠)以及家鼠(褐家鼠)的评估。发现这些啮齿动物的急性经口半数致死量分别为0.10毫克/千克、0.083毫克/千克和0.77毫克/千克。用0.002%和0.005%的溴敌隆进行喂养试验,在沙鼠经过3天的喂养期以及褐家鼠经过4天的喂养期后,产生了100%的死亡率。该抗凝剂在这两种浓度下对所有三个物种均有毒性,但与普通诱饵相比适口性较差。该实验室评估结果表明,0.002%溴敌隆处理过的诱饵可有效用于防治印度大沙鼠、印度沙漠大沙鼠和褐家鼠。