Brooks J E, Htun P T, Naing H
J Hyg (Lond). 1980 Feb;84(1):127-35. doi: 10.1017/s0022172400026619.
The baseline susceptibility of the lesser bandicoot rat, Bandicota bengalensis, from Rangoon, Burma, to five anticoagulant rodenticides was established with no-choice feeding in the laboratory. The susceptibility of lesser bandicoots to the several poisons (brodifacoum, difenacoum, diphacinone, coumatetralyl, and warfarin) was such that they were offered at a 0.001% concentration. B. bengalensis was most susceptible to brodifacoum, and in descending order, difenacoum, coumatetralyl, diphacinone and warfarin. In comparison with Rattus norvegicus on warfarin at 0.005%, B. bengalensis proved more susceptible. Feeding tests at 0.005% concentration indicated that a 1-day feeding on brodifacoum and difenacoum would result in complete mortality, whereas coumatetralyl and warfarin would require 4 days feeding to a 100% kill. Brodifacoum and difenacoum are recommended at 0.002-0.005% bait concentrations and coumatetralyl at 0.005--0.01% concentrations for the control of B. bengalensis in the field in Rangoon. The use of any anticoagulant material in rat control should be alternated with acute toxicants to retard the possible development of anticoagulant resistance.
通过在实验室进行无选择喂食试验,确定了来自缅甸仰光的小板齿鼠(Bandicota bengalensis)对五种抗凝血灭鼠剂的基线敏感性。小板齿鼠对几种毒药(溴敌隆、敌鼠隆、敌鼠、杀鼠迷和华法林)的敏感性使得它们以0.001%的浓度被投喂。小板齿鼠对溴敌隆最敏感,其次是敌鼠隆、杀鼠迷、敌鼠和华法林。与以0.005%浓度的华法林喂食的褐家鼠相比,小板齿鼠更敏感。在0.005%浓度下的喂食试验表明,以溴敌隆和敌鼠隆喂食1天会导致全部死亡,而杀鼠迷和华法林则需要喂食4天才能达到100%致死率。建议在仰光野外控制小板齿鼠时,溴敌隆和敌鼠隆的诱饵浓度为0.002 - 0.005%,杀鼠迷的浓度为0.005 - 0.01%。在灭鼠过程中,任何抗凝血剂的使用都应与急性毒物交替使用,以延缓抗凝血抗性的可能发展。