Klepp O, Dahl O, Stenwig J T
Cancer. 1978 Dec;42(6):2626-30. doi: 10.1002/1097-0142(197812)42:6<2626::aid-cncr2820420618>3.0.co;2-7.
A retrospective study of 53 cases with a histological diagnosis of Kaposi's sarcoma (KS) reported to The Cancer Registry of Norway during a five year period is presented. Four cases were excluded from the material because further information contradicted the diagnosis of KS. Of the remaining 49 cases, information of treatment received before the development of KS was obtained in 41 (83.7%). Six (14.6%) of the 41 patients developed KS during systemic treatment with corticosteroids, two of the 6 cases also used azathioprine. None of the patients had undergone renal transplantation. One additional patient had received radiotherapy for a malignant lymphoma prior to the development of KS. In a control group of 242 consecutive patients hospitalized because of basal cell carcinoma of the skin, none had used systemic corticosteroid or cytotoxic drugs. Case reports of the 7 patients with KS developing after immunopressive therapy are presented.
本文呈现了一项回顾性研究，该研究涉及挪威癌症登记处报告的53例组织学诊断为卡波西肉瘤（KS）的病例，研究时间段为五年。有4例病例被排除在研究材料之外，因为进一步信息与KS诊断相矛盾。在其余49例病例中，41例（83.7%）获得了KS发病前接受治疗的信息。41例患者中有6例（14.6%）在全身使用皮质类固醇治疗期间发生KS，其中2例还使用了硫唑嘌呤。所有患者均未接受过肾移植。另有1例患者在KS发病前因恶性淋巴瘤接受过放疗。在一组因皮肤基底细胞癌连续住院的242例患者的对照组中，无人使用过全身皮质类固醇或细胞毒性药物。本文还介绍了7例免疫抑制治疗后发生KS患者的病例报告。
