Zlateva M, Angelov A
Eksp Med Morfol. 1978;17(4):224-30.
The authors examined the morphological changes in the myocardium of rats with myocardiopathy, caused by electrolytes, steroids and catecholamines. There were fresh and organized microinfarctions, occupying around 17--18% of the volume of the left heart ventricle. Scattered fuxinophilic necrosis were present in the zones outside the infarctions. The electrone microscopic examination of these areas showed vacuolization and crystolisis of mitochondria, dilatation of cysterns of the sarcoplasmic reticulum after dilatation of Z discs of miofibrils and increased folds with herniation of the intercanicular discs. The obtained model belongs to the group of the infarction-like myocardiopathies and resembles the changes in the human myocardium during involvment of the small intramural myocardial arteries and microcirculatory bed.
作者研究了由电解质、类固醇和儿茶酚胺引起的心肌病大鼠心肌的形态学变化。存在新鲜的和机化的微梗死灶，占左心室体积的17%-18%左右。梗死灶外区域有散在的嗜酸性坏死。对这些区域进行电镜检查显示线粒体空泡化和溶解，肌原纤维Z盘扩张后肌浆网池扩张，闰盘褶皱增加并疝出。所获得的模型属于梗死样心肌病组，类似于人类心肌在小壁内心肌动脉和微循环床受累时的变化。
