Sanerkin N G, Watt I
Br J Radiol. 1981 Dec;54(648):1027-33. doi: 10.1259/0007-1285-54-648-1027.
Annular or ring calcification is described in conjunction with fibrous dysplasia in four of 110 patients culled from the Bristol Bone Tumour Registry. This feature results from endochondral calcification and ossification within cartilage rests or chondromata developing pari passu with fibrous dysplasia. Statistically the condition is more likely to be present in the polyostotic form of fibrous dysplasia (17%) than in the monostotic form (circa 1%). All patients were male and the diagnosis of fibrous dysplasia was established between the time of birth and the age of 16. Ring calcification was first detected between the ages of three and 16 years and persisted into adult life. Calcification almost exclusively involved the lower limbs particularly around the knee and above the ankle. In the three polyostotic cases rapid and gross extentsion of the cartilaginous component of the disease occurred at the time of the adolescent growth spurt. When present in a patient with fibrous dysplasia the appearance are typical and signify and associated benign enchondromatous process. No suspicion of chondrosarcoma should arise.
在从布里斯托尔骨肿瘤登记处挑选出的110名患者中，有4名患者的骨纤维发育不良伴有环状钙化。这一特征是由软骨残体或软骨瘤内的软骨内钙化和骨化导致的，与骨纤维发育不良同步发展。从统计学角度来看，这种情况在多骨型骨纤维发育不良中出现的可能性（17%）比单骨型（约1%）更大。所有患者均为男性，骨纤维发育不良的诊断在出生至16岁之间确定。环状钙化最早在3至16岁之间被检测到，并持续至成年期。钙化几乎只累及下肢，尤其是膝盖周围和踝关节上方。在3例多骨型病例中，疾病的软骨成分在青春期生长突增时迅速且广泛地扩展。当骨纤维发育不良患者出现这种表现时，其外观具有典型性，意味着存在相关的良性内生软骨瘤过程。不应怀疑软骨肉瘤。
