γ-羟基丁酸的神经外分布。
The extraneural distribution of gamma-hydroxybutyrate.
作者信息
Nelson T, Kaufman E, Kline J, Sokoloff L
出版信息
J Neurochem. 1981 Nov;37(5):1345-8. doi: 10.1111/j.1471-4159.1981.tb04689.x.
Abstract
gamma-Hydroxybutyrate has been found to be widely distributed in both neural and extraneural tissues in the rat. The kidney and brown fat have more than 10 times higher concentrations of gamma-hydroxybutyrate than does the brain. This observation suggests that gamma-hydroxybutyrate may participate in the metabolism of many organs, and that GABA may not be the precursor in extraneural tissues.
摘要
已发现γ-羟基丁酸在大鼠的神经组织和神经外组织中广泛分布。肾脏和棕色脂肪中的γ-羟基丁酸浓度比大脑中的高10倍以上。这一观察结果表明，γ-羟基丁酸可能参与许多器官的代谢，并且γ-氨基丁酸可能不是神经外组织中的前体。
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