Manicourt D H, Orloff S
J Rheumatol. 1981 Jul-Aug;8(4):613-20.
In a case of polyarthritis after salmonella gastroenteritis the levels of circulating immune complexes (CIC) (C1q-binding assay) correlated closely with disease activity. This observation suggests that systematically absorbed salmonella antigens may lead or contribute to the formation of CIC. CIC activate both the classical and alternate complement pathway and may be important in the pathogenesis of the arthritis associated with salmonella infection.
在一例沙门氏菌胃肠炎后发生的多关节炎病例中，循环免疫复合物（CIC）水平（C1q结合试验）与疾病活动密切相关。这一观察结果表明，系统性吸收的沙门氏菌抗原可能导致或促成CIC的形成。CIC可激活经典和替代补体途径，在与沙门氏菌感染相关的关节炎发病机制中可能起重要作用。
