Di Maio V J, Garriott J C
Forensic Sci Int. 1978 Sep-Oct;12(2):119-25. doi: 10.1016/0379-0738(78)90019-1.
Cocaine is a potent psychotropic drug that alters mood and behavior by stimulating the central nervous system. Deaths from abuse of cocaine are relatively rare. Most such deaths appear to be related to the intravenous injection of the drug. Acute fatal cocaine intoxication is characterized by headache, cold sweats, rapid pulse, tremors and nausea, followed by convulsions, unconsciousness and death. The prime mode of death appears to be respiratory paralysis, secondary to the effects of cocaine on the medullary portion of the brain. This paper presents four deaths due to acute cocaine intoxication following intravenous injection. Blood concentrations of cocaine were 0.11, 0.37, 0.36 and 0.75 mg/dl.
可卡因是一种强效精神药物，通过刺激中枢神经系统来改变情绪和行为。因滥用可卡因导致的死亡相对较少。大多数此类死亡似乎与静脉注射该药物有关。急性致命性可卡因中毒的特征是头痛、冷汗、脉搏加快、震颤和恶心，随后出现抽搐、昏迷和死亡。主要死亡方式似乎是呼吸麻痹，这是可卡因对脑髓质部分产生影响的继发后果。本文介绍了4例静脉注射后因急性可卡因中毒导致的死亡病例。可卡因的血药浓度分别为0.11、0.37、0.36和0.75毫克/分升。
