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糖尿病遗传因素对高龄糖尿病患者心血管风险特征的影响(作者译)

[The influence of diabetes heredity on cardiovasculary risk profile in patients with high age diabetes (author's transl)].

作者信息

Schneider H, Ziegelasch H J

出版信息

Z Alternsforsch. 1981;36(2):137-41.

PMID:7303731
Abstract

The cardiovasculary risk profile of 105 newly detected, but still untreated, high age diabetics with an average of 69,1 years showing diabetes heredity in relatives of first degree was compared with a corresponding group (same age and same number of patients) without diabetes heredity. Taking into consideration exclusively the danger magnitudes overweight, hypertension, hypertriglyceridaemia, hypercholesterolaemia and hyperuricaemia, one sees an identical risk profile for both groups (the groups of patients were chosen according the principle of biostatistical gemini forming). For the showing of pathogenic magnitudes of influence within the metabolic syndrome the environmental factors seem to have a far greater importance than hereditary diabetogenic ones.

摘要

对105名新确诊但仍未接受治疗的高龄糖尿病患者(平均年龄69.1岁,有一级亲属糖尿病遗传史)的心血管风险状况,与一组相应的(年龄相同、患者数量相同)无糖尿病遗传史的人群进行了比较。仅考虑超重、高血压、高甘油三酯血症、高胆固醇血症和高尿酸血症等危险因素,两组的风险状况相同(患者组是根据生物统计学双胞胎形成原则选取的)。对于代谢综合征中致病影响因素的表现,环境因素似乎比遗传性糖尿病因素重要得多。

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