Schaul N, Lueders H, Sachdev K
Arch Neurol. 1981 Nov;38(11):690-2. doi: 10.1001/archneur.1981.00510110050006.
Forty-two patients who had bursts of spontaneous, bilaterally synchronous slow waves during the waking state in an otherwise normal EEG were compared with 42 age-matched control subjects with normal EEGs. The study group had a significantly higher incidence of diffuse encephalopathy than did the control group. They also had a higher incidence of alterations of consciousness. None of the patients in the study group had focal, deep midline lesions. This study indicates that generalized, bilaterally synchronous slow bursts in the EEG are significant abnormalities that in the majority of cases are associated with a mild to moderate diffuse encephalopathy rather than with a lesion limited to deep midline structures.
42例在清醒状态下脑电图（EEG）其他方面正常但出现双侧同步性慢波阵发的患者与42例年龄匹配、EEG正常的对照受试者进行了比较。研究组弥漫性脑病的发生率显著高于对照组。他们意识改变的发生率也更高。研究组中没有患者有局灶性、深部中线病变。这项研究表明，EEG中双侧同步性慢波阵发是显著异常，在大多数情况下与轻度至中度弥漫性脑病相关，而非与局限于深部中线结构的病变相关。
