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“高危”人群中结直肠癌的低发病率:其与饮食习惯的相关性。

The low incidence of colorectal cancer in a "high-risk" population: its correlation with dietary habits.

作者信息

Rozen P, Hellerstein S M, Horwitz C

出版信息

Cancer. 1981 Dec 15;48(12):2692-5. doi: 10.1002/1097-0142(19811215)48:12<2692::aid-cncr2820481222>3.0.co;2-l.

DOI:10.1002/1097-0142(19811215)48:12<2692::aid-cncr2820481222>3.0.co;2-l
PMID:7306925
Abstract

In Israel, the incidence of colorectal cancer is highest in European-American-born Jews, although this incidence is lower than that found in European-born Jews living in the United States. A significantly lower-than-expected incidence was found in a specific kibbutz established by immigrants of European origin. Matched population samples from this kibbutz and the city of Tel Aviv revealed significant differences in dietary habits. The kibbutz members ate more unavailable carbohydrate and ascorbic acid and had a higher dietary polyunsaturated to saturated fat (P/S) ratio than the city dwellers. Both groups ate more crude fiber, less saturated fat, and less beef than has been reported from American and European countries. This kibbutz diet seems to have prevented large bowel cancer, parallels the "prudent" diet of Wynder, and possibly indicates the feasibility of colorectal cancer prevention.

摘要

在以色列,欧美裔出生的犹太人患结直肠癌的发病率最高,尽管这一发病率低于生活在美国的欧洲裔出生的犹太人。在一个由欧洲裔移民建立的特定集体农场中,发现发病率显著低于预期。来自这个集体农场和特拉维夫市的匹配人群样本显示,饮食习惯存在显著差异。集体农场成员摄入的不可利用碳水化合物和抗坏血酸更多,饮食中多不饱和脂肪与饱和脂肪的比例(P/S)高于城市居民。与美国和欧洲国家报道的情况相比,两组摄入的膳食纤维都更多,饱和脂肪和牛肉更少。这种集体农场饮食似乎预防了大肠癌,与温德的“谨慎”饮食相似,并且可能表明预防结直肠癌是可行的。

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The low incidence of colorectal cancer in a "high-risk" population: its correlation with dietary habits.“高危”人群中结直肠癌的低发病率:其与饮食习惯的相关性。
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引用本文的文献

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Genetic factors and colorectal cancer in Ashkenazi Jews.阿什肯纳兹犹太人的遗传因素与结直肠癌
Fam Cancer. 2004;3(3-4):215-21. doi: 10.1007/s10689-004-9547-x.
2
Faecal pH, dietary fibre intake, and proneness to colon cancer in four South African populations.南非四个群体的粪便pH值、膳食纤维摄入量与结肠癌易感性
Br J Cancer. 1986 Apr;53(4):489-95. doi: 10.1038/bjc.1986.77.
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The causes and management of lower GI bleeding: a study based on clinical observations at Hanyang University Hospital.下消化道出血的病因与管理:基于汉阳大学医院临床观察的一项研究
Gastroenterol Jpn. 1991 Jul;26 Suppl 3:101-6. doi: 10.1007/BF02779275.