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Suppression of Clostridium difficile by normal hamster cecal flora and prevention of antibiotic-associated cecitis.正常仓鼠盲肠菌群对艰难梭菌的抑制作用及抗生素相关性盲肠炎的预防
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本文引用的文献

1
INTESTINAL MICROFLORA OF NORMAL HAMSTERS.正常仓鼠的肠道微生物群
Lab Anim Care. 1965 Jun;15:185-93.
2
Susceptibility of anaerobic bacteria in vitro to 23 antimicrobial agents.厌氧细菌在体外对23种抗菌药物的敏感性
Chemotherapy. 1980;26(5):344-53. doi: 10.1159/000237926.
3
Rapid microassay of gentamicin, kanamycin, neomycin, streptomycin, and vancomycin in serum or plasma.血清或血浆中庆大霉素、卡那霉素、新霉素、链霉素和万古霉素的快速微量测定。
J Lab Clin Med. 1971 Sep;78(3):457-63.
4
The role of the intestinal microflora in experimental colitis.肠道微生物群在实验性结肠炎中的作用。
Am J Clin Nutr. 1977 Nov;30(11):1819-25. doi: 10.1093/ajcn/30.11.1819.
5
Clindamycin-induced enterocolitis in hamsters.仓鼠中克林霉素诱导的小肠结肠炎
J Infect Dis. 1978 Apr;137(4):464-75. doi: 10.1093/infdis/137.4.464.
6
Identification of Clostridium difficile as a cause of pseudomembranous colitis.艰难梭菌被鉴定为伪膜性结肠炎的病因。
Br Med J. 1978 Mar 18;1(6114):695. doi: 10.1136/bmj.1.6114.695.
7
Antibiotic-associated colitis: effects of antibiotics on Clostridium difficile and the disease in hamsters.抗生素相关性结肠炎：抗生素对艰难梭菌及仓鼠疾病的影响。
Rev Infect Dis. 1979 Mar-Apr;1(2):386-97. doi: 10.1093/clinids/1.2.386.
8
Selective and differential medium for isolation of Clostridium difficile.用于分离艰难梭菌的选择性和鉴别性培养基。
J Clin Microbiol. 1979 Feb;9(2):214-9. doi: 10.1128/jcm.9.2.214-219.1979.
9
Randomised controlled trial of vancomycin for pseudomembranous colitis and postoperative diarrhoea.万古霉素治疗伪膜性结肠炎和术后腹泻的随机对照试验。
Br Med J. 1978 Dec 16;2(6153):1667-9. doi: 10.1136/bmj.2.6153.1667.
10
Antibiotic-induced colitis implication of a toxin neutralised by Clostridium sordellii antitoxin.抗生素诱导的结肠炎与一种被索氏梭菌抗毒素中和的毒素有关。
Lancet. 1977 Nov 26;2(8048):1103-6. doi: 10.1016/s0140-6736(77)90547-5.

正常仓鼠盲肠菌群对艰难梭菌的抑制作用及抗生素相关性盲肠炎的预防

Suppression of Clostridium difficile by normal hamster cecal flora and prevention of antibiotic-associated cecitis.

作者信息

Wilson K H, Silva J, Fekety F R

出版信息

Infect Immun. 1981 Nov;34(2):626-8. doi: 10.1128/iai.34.2.626-628.1981.

DOI:10.1128/iai.34.2.626-628.1981
PMID:7309245
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC350912/
Abstract

Administration of normal cecal homogenates decreased numbers of viable Clostridium difficile and prevented cecitis in antibiotic-challenged hamsters. Cecal anaerobes appeared to suppress C. difficile.

摘要

给予正常盲肠匀浆可减少艰难梭菌的活菌数量，并预防抗生素处理的仓鼠发生盲肠炎。盲肠厌氧菌似乎可抑制艰难梭菌。