Bhai I, Pandey A K
J Helminthol. 1981 Dec;55(4):295-305. doi: 10.1017/s0022149x00027905.
Remarkable hypertrophic changes were observed in the adrenal and thyroid glands of male mice after 7 to 16 days of infection with the filariform larvae of Ancylostoma caninum, but not in females. The adrenal gland revealed enormous enlargement of cells in the zonae glomerulosa, fasciculata and medulla, and also the formation of big vacuoles in the glomerular zone, whereas the thyroid gland showed distinctly hypertrophied follicular epithelium with marked acolloidal condition and follicular mass formation. These changes in the cellular diameter were highly significant (P greater than 0.001 to less than 0.005). The possible reasons for hyperactivity of these glands are discussed.
在用犬钩虫丝状蚴感染雄性小鼠7至16天后，观察到其肾上腺和甲状腺出现显著的肥大变化，而雌性小鼠则未出现。肾上腺显示球状带、束状带和髓质的细胞大幅增大，球状带还形成了大液泡，而甲状腺则表现为滤泡上皮明显肥大，伴有明显的胶体状态和滤泡团块形成。这些细胞直径的变化具有高度显著性（P大于0.001至小于0.005）。文中讨论了这些腺体功能亢进的可能原因。
