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胸腔镜检查在肺癌临床评估及分期中的应用

Pleuroscopy in clinical evaluation and staging of lung cancer.

作者信息

Weissberg D, Kaufman M, Schwecher I

出版信息

Poumon Coeur. 1981;37(4):241-3.

PMID:7312752
Abstract

The use of pleuroscopy in patients with bronchogenic carcinoma has not been reported previously. We performed this procedure in 45 lung cancer patients in whom pleural involvement was suspected. Pleural fluid or mestastases were found in 37 patients, 5 of whom had also major atelectasis due to bronchial obstruction by tumor. Neoplasm penetrating vital structures (aorta, brachial plexus) was found in 3 patients, tumor confining to resectable structures in 3; no pleural abnormalities were disclosed in 2. Based on these findings, 43 tumors were assigned stage III. Only on two occasions pleuroscopy did not aid staging. In 20 patients with massive pleural effusion causing dyspnea we insufflated talc in order to produce pleurodesis. This was fully successful in 16 patients, while in 2 the pleural cavity became only partially obliterated, with symptomatic relief. In 2 patients pleurodesis could not be evaluated because of early death caused by progression of cancer. Pleuroscopy is a highly informative procedure, applicable when involvement of pleura by lung cancer is suspected. It is helpful in clinical staging of the tumor and in assessment of its resectability, particularly in elderly, poor-risk patients. It provides the best way for talc insufflation when pleurodesis is indicated. Pleuroscopy should have an established place in the clinical evaluation and staging of lung cancer.

摘要

此前尚未有关于在支气管源性癌患者中使用胸腔镜检查的报道。我们对45例疑似有胸膜受累的肺癌患者进行了该操作。在37例患者中发现了胸腔积液或转移灶,其中5例还因肿瘤导致支气管阻塞而出现大片肺不张。3例患者发现肿瘤侵犯重要结构(主动脉、臂丛神经),3例肿瘤局限于可切除结构;2例未发现胸膜异常。基于这些发现,43例肿瘤被判定为III期。仅在两次检查中胸腔镜检查对分期没有帮助。在20例因大量胸腔积液导致呼吸困难的患者中,我们注入滑石粉以产生胸膜固定术。16例患者完全成功,2例胸膜腔仅部分闭塞,但症状缓解。2例患者因癌症进展导致早期死亡,无法评估胸膜固定术的效果。胸腔镜检查是一种信息量很大的操作,适用于疑似肺癌累及胸膜的情况。它有助于肿瘤的临床分期及其可切除性的评估,特别是对于老年、高危患者。当需要进行胸膜固定术时,它为注入滑石粉提供了最佳途径。胸腔镜检查在肺癌的临床评估和分期中应占有一席之地。

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