Kyrönseppä H, Pettersson T
Scand J Infect Dis. 1981;13(4):311-2. doi: 10.3109/inf.1981.13.issue-4.16.
50 patients with giardiasis were treated with either metronidazole or tinidazole in random order according to a code. 25 patients received 2.0 g metronidazole on 2 consecutive days; 19 were cured (76%); 7 patients complained of mild side-effects. 25 patients received tinidazole 2.0 g as a single dose, and 22 were cured (88%); 5 patients complained of mild side-effects. The difference between the results of the two regimens was not statistically significant. A 1-week course of metronidazole (200 mg 3 times daily) was successful in 8/9 failures; 1 patient was finally cured with mepacrine.
50例贾第虫病患者按照随机编码顺序分别接受甲硝唑或替硝唑治疗。25例患者连续2天每日服用2.0克甲硝唑，其中19例治愈（76%），7例患者抱怨有轻微副作用。25例患者单次服用2.0克替硝唑，22例治愈（88%），5例患者抱怨有轻微副作用。两种治疗方案的结果差异无统计学意义。甲硝唑1周疗程（每日3次，每次200毫克）使9例治疗失败患者中的8例获得成功；1例患者最终用阿的平治愈。
