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各种药物治疗贾第虫病的疗效。一项对比研究。

Efficacy of various drugs for treatment of giardiasis. A comparative study.

作者信息

Levi G C, de Avila C A, Amato Neto V

出版信息

Am J Trop Med Hyg. 1977 May;26(3):564-5. doi: 10.4269/ajtmh.1977.26.564.

Abstract

A total of 172 patients with giardiasis were treated with four of the drugs most commonly used for this infection. All drugs were used in their usual posologic schedules. The cure rates achieved with furazolidone, nimorazole, metronidazole, and tinidazole were; respectively, 72%, 94%, 87%, and 97%, while in a control group given no medication stools of only 35% of the patients became negative. Side effects were of minor importance in patients treated with nimorazole and metronidazole, and were somewhat more frequent and severe in those treated with furazolidone. Tinidazole produced no side effects.

摘要

共有172例贾第虫病患者接受了治疗该感染最常用的四种药物中的一种治疗。所有药物均按照常规剂量方案使用。呋喃唑酮、硝唑咪、甲硝唑和替硝唑的治愈率分别为72%、94%、87%和97%,而在未用药的对照组中,只有35%的患者粪便检测呈阴性。硝唑咪和甲硝唑治疗的患者副作用较轻,呋喃唑酮治疗的患者副作用稍多且更严重。替硝唑未产生副作用。

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