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幼犬对肺切除术的适应性反应。

Adaptive response to pneumonectomy in puppies.

作者信息

Thurlbeck W M, Galaugher W, Mathers J

出版信息

Thorax. 1981 Jun;36(6):424-7. doi: 10.1136/thx.36.6.424.

DOI:10.1136/thx.36.6.424
PMID:7314013
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC471527/
Abstract

When left pneumonectomy was performed on 9-week-old puppies, the right lung increased in weight, volume, surface area, and number of alveoli so that at age 20 weeks these variables were the same as those of both lungs of control animals and significantly larger than those of the right lung of control animals. The adaptive response of the right lung after pneumonectomy was greater in the lower lobe than in the middle or cardiac lobes. The number of alveoli per ml and the average interalveolar wall distance, hence the surface to volume ratio, was the same in both lungs of control animals and the same in the cardiac, middle, and lower lobes of their right lungs.

摘要

对9周龄幼犬进行左肺切除术后,右肺的重量、体积、表面积和肺泡数量均增加,以至于在20周龄时,这些变量与对照动物双肺的变量相同,且显著大于对照动物右肺的变量。肺切除术后右肺的适应性反应在下叶比中叶或心叶更明显。对照动物双肺每毫升的肺泡数量和平均肺泡壁间距(即表面积与体积之比)相同,其右肺的心叶、中叶和下叶也相同。

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1
Adaptive response to pneumonectomy in puppies.幼犬对肺切除术的适应性反应。
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本文引用的文献

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Calculation of the internal surface of a lung.肺内表面的计算。
Nature. 1952 Jul 19;170(4316):116-7.
2
Serum from pneumonectomized rabbits stimulates alveolar type II cell proliferation in vitro.来自肺切除兔子的血清在体外刺激II型肺泡细胞增殖。
Am Rev Respir Dis. 1980 Apr;121(4):701-7. doi: 10.1164/arrd.1980.121.4.701.
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Morphometric analysis of late adaptation of the residual lung following pneumonectomy in young and adult rabbits.幼兔和成年兔肺切除术后残肺晚期适应性的形态计量学分析
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[Growth and regeneration of lungs (experimental research)].[肺的生长与再生(实验研究)]
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Morphogenetic and proliferative changes in the regenerating lung of the rat.大鼠再生肺中的形态发生和增殖变化。
Anat Rec. 1973 Aug;176(4):389-95. doi: 10.1002/ar.1091760403.
6
Compensatory pulmonary hypertrophy after incapacitation of one lung in the rat.大鼠一侧肺丧失功能后的代偿性肺肥大。
J Thorac Cardiovasc Surg. 1973 Jul;66(1):147-52.
7
The postnatal growth of the rat lung. I. Morphometry.大鼠肺的出生后生长。I. 形态测量学。
Anat Rec. 1974 Apr;178(4):711-30. doi: 10.1002/ar.1091780405.
8
Stimulation of cell division following unilateral collapse of the lung.单侧肺萎陷后细胞分裂的刺激
Anat Rec. 1974 Dec;180(4):681-6. doi: 10.1002/ar.1091800412.
9
Adaptive growth of the lung following pneumonectomy in rats.大鼠肺切除术后肺的适应性生长
J Appl Physiol. 1974 Oct;37(4):491-5. doi: 10.1152/jappl.1974.37.4.491.
10
Lung growth after unilateral pneumonectomy: quantitation of collagen synthesis and content.单侧肺切除术后肺的生长:胶原合成与含量的定量分析
Am Rev Respir Dis. 1975 Mar;111(3):267-77. doi: 10.1164/arrd.1975.111.3.267.