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幼犬对肺切除术的适应性反应。

Adaptive response to pneumonectomy in puppies.

作者信息

Thurlbeck W M, Galaugher W, Mathers J

出版信息

Thorax. 1981 Jun;36(6):424-7. doi: 10.1136/thx.36.6.424.

Abstract

When left pneumonectomy was performed on 9-week-old puppies, the right lung increased in weight, volume, surface area, and number of alveoli so that at age 20 weeks these variables were the same as those of both lungs of control animals and significantly larger than those of the right lung of control animals. The adaptive response of the right lung after pneumonectomy was greater in the lower lobe than in the middle or cardiac lobes. The number of alveoli per ml and the average interalveolar wall distance, hence the surface to volume ratio, was the same in both lungs of control animals and the same in the cardiac, middle, and lower lobes of their right lungs.

摘要

对9周龄幼犬进行左肺切除术后,右肺的重量、体积、表面积和肺泡数量均增加,以至于在20周龄时,这些变量与对照动物双肺的变量相同,且显著大于对照动物右肺的变量。肺切除术后右肺的适应性反应在下叶比中叶或心叶更明显。对照动物双肺每毫升的肺泡数量和平均肺泡壁间距(即表面积与体积之比)相同,其右肺的心叶、中叶和下叶也相同。

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