Hürter T, Mennel H D
Acta Neuropathol. 1981;55(2):105-11. doi: 10.1007/BF00699235.
In this study an experimental intracerebral tumor has been investigated with special consideration of structures, which may be involved in edema production and/or resolution. For this purpose a cloned tumor cell line (RG1 2.2) has been injected stereotactically into the brain of BD-IX rats. The tumor has some characteristics in common with low differentiated oligodendroglioma in men. A honeycomb architecture may be seen in the center of the tumor. It is built up by rounded or elongated cells, which can be impregnated in parts. In the central area, cells exhibit a voluminous digestive apparatus, composed of dictyosomes, vesicles, and some vacuoles with a membranaceous or homogeneous content. Tumor cells in the periphery show large processes and a small digestive apparatus. The sinusoidal tumor vessels are composed of an endothelium with many vesicles but no openings.
在本研究中，对一种实验性脑内肿瘤进行了研究，特别考虑了可能参与水肿产生和/或消退的结构。为此，将一种克隆的肿瘤细胞系（RG1 2.2）立体定向注射到BD-IX大鼠的脑内。该肿瘤具有一些与人类低分化少突胶质细胞瘤相同的特征。在肿瘤中心可见蜂窝状结构。它由圆形或细长形细胞构成，部分细胞可被浸染。在中心区域，细胞具有大量的消化细胞器，由高尔基体、囊泡和一些含有膜状或均质内容物的液泡组成。周边的肿瘤细胞显示出大的突起和较小的消化细胞器。肿瘤的窦状血管由具有许多囊泡但无开口的内皮组成。
