疥疮和屋尘螨的共同抗原。

Antigens Common to Scabies and House dust Mites.

作者信息

Falk E S, Dale S, Bolle R, Haneberg B

出版信息

Allergy. 1981 May;36(4):233-8. doi: 10.1111/j.1398-9995.1981.tb01568.x.

DOI:10.1111/j.1398-9995.1981.tb01568.x

Abstract

Twenty-five antigens were demonstrated in a crude Dermatophagoides farinae (DF) extract by means of crossed immunoelectrophoresis (CIE), using a rabbit anti-DF serum. With the same antiserum, four antigens were demonstrated in a scabies mite preparations, indicating an immunological relationship between these scabies antigens and some of the DF antigens. In tandem CIE experiments the DF antigens were found to be partly identical to three of the scabies antigens. No IgE activity against any of these scabies antigens was evident in pooled sera from patients with house dust mite allergy by crossed radioimmunoelectrophoresis. However, one such patient had IgE antibodies to a DF antigen and a partial identical scabies antigen.

摘要

利用兔抗粉尘螨血清，通过交叉免疫电泳（CIE）在粗制的粉尘螨（DF）提取物中检测到了25种抗原。使用相同的抗血清，在疥螨制剂中检测到了4种抗原，这表明这些疥螨抗原与部分DF抗原之间存在免疫关系。在串联CIE实验中，发现DF抗原与三种疥螨抗原部分相同。通过交叉放射免疫电泳，在家尘螨过敏患者的混合血清中未发现针对任何这些疥螨抗原的IgE活性。然而，有一名此类患者对一种DF抗原和一种部分相同的疥螨抗原有IgE抗体。