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屋尘螨(粉尘螨)和腐食酪螨的交叉抗原性及变应原特性

Cross antigenic and allergenic properties of the house dust mite Dermatophagoides farinae and the storage mite Tyrophagus putrescentiae.

作者信息

Arlian L G, Geis D P, Vyszenski-Moher D L, Bernstein I L, Gallagher J S

出版信息

J Allergy Clin Immunol. 1984 Aug;74(2):172-9. doi: 10.1016/0091-6749(84)90282-3.

Abstract

The crossed antigenicity and allergenicity of the storage mite Tyrophagus putrescentiae (TP) and the house dust mite Dermatophagoides farinae (DF) were characterized by means of crossed immunoelectrophoresis and crossed radioimmunoelectrophoresis. DF extracts exhibited 32 antigens and as many as eight were demonstrated to be allergens. DF feces exhibited 20 antigens and six of these were allergens. Twenty antigens and two allergens were demonstrated for TP. Two antigenic and allergenic determinants were shared by DF and TP, and two determinants were also shared by DF feces and TP feces. TP feces and DF shared two antigenic and allergenic determinants. Our results demonstrated that the two mites and their feces extracts contain multiple antigens and allergens.

摘要

通过交叉免疫电泳和交叉放射免疫电泳对储藏螨腐食酪螨(TP)和屋尘螨粉尘螨(DF)的交叉抗原性和变应原性进行了表征。DF提取物显示出32种抗原,其中多达8种被证明是变应原。DF粪便显示出20种抗原,其中6种是变应原。TP显示出20种抗原和2种变应原。DF和TP共有两种抗原性和变应原性决定簇,DF粪便和TP粪便也共有两种决定簇。TP粪便和DF共有两种抗原性和变应原性决定簇。我们的结果表明,这两种螨及其粪便提取物含有多种抗原和变应原。

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