Anke H, Kemmer T, Höfle G
J Antibiot (Tokyo). 1981 Aug;34(8):923-8. doi: 10.7164/antibiotics.34.923.
Five structurally related, angular azaphilones, the deflectins, were isolated from the mycelia of Aspergillus deflectus. The structures of all compounds have been established. Besides the inhibitory effects on the growth of bacteria and fungi, these compounds showed lytic activity towards bacteria and erythrocytes and cytotoxic activity towards cells of the ascitic form of Ehrlich carcinoma of mice. The inhibitory effects of the deflectins could be reversed by the addition of serum or serum albumin.
从偏斜曲霉的菌丝体中分离出了五种结构相关的角氮杂蒽酮类化合物，即偏斜菌素。所有化合物的结构均已确定。除了对细菌和真菌的生长有抑制作用外，这些化合物还对细菌和红细胞表现出裂解活性，对小鼠艾氏腹水癌腹水形式的细胞具有细胞毒性活性。添加血清或血清白蛋白可逆转偏斜菌素的抑制作用。
