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pH对脂质抑制金黄色葡萄球菌携带质粒培养物的影响。

Effect of pH on inhibition of plasmid-carrying cultures of Staphylococcus aureus by lipids.

作者信息

Naidoo J

出版信息

J Gen Microbiol. 1981 May;124(1):173-9. doi: 10.1099/00221287-124-1-173.

DOI:10.1099/00221287-124-1-173
PMID:7320698
Abstract

The inhibition of Staphylococcus aureus by fatty acids was pH dependent. The inhibitory properties of myristic acid were greater at pH 5.5 than at pH 7, whereas those of linoleic acid were less at pH 5.5 than at pH 7. Seven clinical penicillin-resistant cultures survived better in the presence of linoleic acid at pH 5.5 than did their sensitive counterparts. The resistance to linoleic acid in most plasmid-carrying cultures at pH 5.5 was probably not due to the production of penicillinase, but to some other determinants carried by the plasmid.

摘要

脂肪酸对金黄色葡萄球菌的抑制作用依赖于pH值。肉豆蔻酸在pH 5.5时的抑制特性比在pH 7时更强,而亚油酸在pH 5.5时的抑制特性比在pH 7时更弱。七种临床耐青霉素培养物在pH 5.5的亚油酸存在下比其敏感对应物存活得更好。大多数携带质粒的培养物在pH 5.5时对亚油酸的抗性可能不是由于青霉素酶的产生,而是由于质粒携带的一些其他决定因素。

相似文献

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Effect of pH on inhibition of plasmid-carrying cultures of Staphylococcus aureus by lipids.pH对脂质抑制金黄色葡萄球菌携带质粒培养物的影响。
J Gen Microbiol. 1981 May;124(1):173-9. doi: 10.1099/00221287-124-1-173.
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Mechanism of the inhibitory action of linoleic acid on the growth of Staphylococcus aureus.
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引用本文的文献

1
The selection of penicillin-resistant staphylococci on murine skin.小鼠皮肤上耐青霉素葡萄球菌的筛选。
Br J Exp Pathol. 1983 Apr;64(2):211-4.
2
Strategies for typing and properties of epidemic methicillin-resistant Staphylococcus aureus.耐甲氧西林金黄色葡萄球菌流行株的分型策略及特性
Eur J Clin Microbiol. 1986 Dec;5(6):702-9. doi: 10.1007/BF02013309.