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药物不良反应的预防——药剂师在基层医疗团队中能否发挥潜在作用?

The prevention of adverse drug reactions--a potential role for pharmacists in the primary care team?

作者信息

Shulman J I, Shulman S, Haines A P

出版信息

J R Coll Gen Pract. 1981 Jul;31(228):429-34.

Abstract

Medication record cards were kept for 1,366 patients over a three-year period at a neighbourhood pharmacy in north-west London. Eighty-six potential adverse drug reactions were detected. In 53 cases the general practitioner changed the prescription after being contacted by the pharmacist. In a further 15 cases advice intended to reduce the likelihood of an adverse drug reaction was given to the patients by the pharmacist. Seventy-six errors on prescriptions were also detected; these were mainly unintended changes in dose or strength of medication. Pharmacists could have a useful role to play in monitoring for potential drug reactions in general practice. Closer collaboration between the two professions would be of mutual benefit.

摘要

在伦敦西北部的一家社区药房,三年内为1366名患者保存了用药记录卡。检测到86起潜在的药物不良反应。在53例中,药剂师联系全科医生后,医生更改了处方。在另外15例中,药剂师向患者提供了旨在降低药物不良反应可能性的建议。还检测到76处处方错误;这些主要是药物剂量或强度的意外变化。药剂师在监测全科医疗中的潜在药物反应方面可以发挥有益作用。这两个专业之间更密切的合作将互利共赢。

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本文引用的文献

2
Preventable drug reactions--causes and cures.可预防的药物不良反应——成因与治疗方法
N Engl J Med. 1971 Jun 17;284(24):1361-8. doi: 10.1056/NEJM197106172842408.
8
Adverse drug reactions-a matter of opinion.药物不良反应——一个见仁见智的问题。
Clin Pharmacol Ther. 1976 May;19(5 Pt 1):489-92. doi: 10.1002/cpt1976195part1489.

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