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体育锻炼期间人体红细胞中的葡萄糖利用情况。

Glucose utilization in human erythrocytes during physical exercise.

作者信息

Fornaini G, Dachà M, Accorsi A, Fazi A, Piatti E

出版信息

Med Sci Sports Exerc. 1981;13(5):322-4.

PMID:7321830
Abstract

Red blood cells obtained from well-trained athletes consumed glucose at a higher rate than those from sedentary subjects when incubated in vitro in a glucose containing medium at 37 degrees C. Similar results were obtained when fructose was substituted for glucose, but not when galactose was the monosaccharide. The utilization of glucose by erythrocytes can occur both via the Embden-Meyerhof and Pentose phosphate pathways (PPP). In the present experiments, there were no differences in the activities of select enzymes in these pathways or in metabolic intermediates of the erythrocytes. An exception was an elevated 2,3-diphosphoglycerate (2,3DPG) in the erythrocytes of the athletes. Additional experiments are needed to identify changes in the red blood cells of the athletes which produce the increased consumption of glucose.

摘要

当在37摄氏度的含葡萄糖培养基中进行体外培养时,训练有素的运动员的红细胞消耗葡萄糖的速率高于久坐不动的受试者的红细胞。用果糖替代葡萄糖时也得到了类似的结果,但当单糖为半乳糖时则不然。红细胞对葡萄糖的利用可通过糖酵解途径和磷酸戊糖途径(PPP)进行。在本实验中,这些途径中特定酶的活性或红细胞的代谢中间产物并无差异。一个例外是运动员红细胞中2,3-二磷酸甘油酸(2,3DPG)升高。需要进行更多实验来确定运动员红细胞中导致葡萄糖消耗增加的变化。

相似文献

1
Glucose utilization in human erythrocytes during physical exercise.体育锻炼期间人体红细胞中的葡萄糖利用情况。
Med Sci Sports Exerc. 1981;13(5):322-4.
2
Erythrocyte 2,3-diphosphoglycerate and serum enzyme concentrations in trained and sedentary men.训练有素和久坐不动男性的红细胞2,3 - 二磷酸甘油酸及血清酶浓度
Med Sci Sports Exerc. 1986 Apr;18(2):174-9.
3
[Effect of physical exercise on glycolysis in human red blood cells (author's transl)].体育锻炼对人体红细胞糖酵解的影响(作者译)
Hokkaido Igaku Zasshi. 1978 May;53(3):221-37.
4
Effects of dibutyryl-cANP on glycolysis in washed human erythrocytes.
Acta Biol Med Ger. 1981;40(7-8):999-1002.
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Metabolic alterations in the human erythrocyte produced by increases in glucose concentration. The role of the polyol pathway.葡萄糖浓度升高引起的人体红细胞代谢改变。多元醇途径的作用。
J Clin Invest. 1971 Oct;50(10):2104-12. doi: 10.1172/JCI106704.
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Erythrocyte metabolic alterations in type I diabetes: relationship to metabolic control.
Ann Biol Clin (Paris). 1992;50(1):9-13.
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Bovine post-parturient haemoglobinuria: effect of inorganic phosphate on red cell metabolism.牛产后血红蛋白尿:无机磷酸盐对红细胞代谢的影响
Res Vet Sci. 1985 Nov;39(3):333-9.
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[Energy metabolism in the erythrocytes of humans exposed to anti-orthostatic hypokinesia].[暴露于抗直立性运动减少状态下的人体红细胞中的能量代谢]
Kosm Biol Aviakosm Med. 1988 May-Jun;22(3):39-41.
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NADPH production in the oxidative pentose phosphate pathway as source of reducing equivalents in glycolysis of human red cells in vitro.体外人红细胞糖酵解中作为还原当量来源的氧化戊糖磷酸途径中的NADPH生成
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引用本文的文献

1
The activity of erythrocyte enzymes in rats subjected to running exercises.
Eur J Appl Physiol Occup Physiol. 1985;54(5):533-7. doi: 10.1007/BF00422965.
2
Red cell 2,3-DPG, ATP, and mean cell volume in highly trained athletes. Effect of long-term submaximal exercise.高水平运动员的红细胞2,3-二磷酸甘油酸、三磷酸腺苷及平均红细胞体积。长期次最大强度运动的影响。
Eur J Appl Physiol Occup Physiol. 1985;53(4):334-8. doi: 10.1007/BF00422849.
3
Effects of training on erythrocyte 2,3-diphosphoglycerate in normal men.训练对正常男性红细胞2,3 - 二磷酸甘油酸的影响。
Eur J Appl Physiol Occup Physiol. 1988;57(4):456-61. doi: 10.1007/BF00417993.