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直接血培养纸片扩散法抗菌药物敏感性试验的评估

Evaluation of a direct blood culture disk diffusion antimicrobial susceptibility test.

作者信息

Doern G V, Scott D R, Rashad A L, Kim K S

出版信息

Antimicrob Agents Chemother. 1981 Nov;20(5):696-8. doi: 10.1128/AAC.20.5.696.

Abstract

A total of 556 unique blood culture isolates of nonfastidious aerobic and facultatively anaerobic bacteria were examined by direct and standardized disk susceptibility test methods (4,234 antibiotic-organism comparisons). When discrepancies which could be accounted for by the variability inherent in disk diffusion susceptibility tests were excluded, the direct method demonstrated 96.8% overall agreement with the standardized method. A total of 1.6% minor, 1.5% major, and 0.1% very major discrepancies were noted.

摘要

通过直接和标准化纸片药敏试验方法(4234次抗生素-菌株比较)对总共556株非苛养需氧菌和兼性厌氧菌的血培养分离株进行了检测。当排除由纸片扩散药敏试验固有变异性导致的差异后,直接法与标准化方法的总体一致性为96.8%。共发现1.6%的轻微差异、1.5%的主要差异和0.1%的非常主要差异。

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