肝损伤对饥饿大鼠酮体生成及氮平衡的影响。
Effects of liver damage on ketone-body production and nitrogen balance in starved rats.
作者信息
Flatt J P, Quail J M
出版信息
Biochem J. 1981 Jul 15;198(1):227-30. doi: 10.1042/bj1980227.
Abstract
The metabolic effects of intraperitoneal administration of carbon tetrachloride (1ml/kg) were studied in starved rats. The most notable change in circulating substrates was an 80% fall in ketone-body concentrations, which was associated with the doubling of urinary nitrogen losses. The results demonstrate the importance of starvation ketosis in permitting fat mobilization to decrease effectively protein losses during starvation.
摘要
在饥饿的大鼠中研究了腹腔注射四氯化碳（1毫升/千克）的代谢效应。循环底物中最显著的变化是酮体浓度下降80%，这与尿氮损失增加一倍有关。结果表明，饥饿性酮症在饥饿期间允许脂肪动员以有效减少蛋白质损失方面具有重要作用。
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