Sato T, Koyama K, Yamauchi H, Matsuno S
Gastroenterol Jpn. 1981;16(5):459-64. doi: 10.1007/BF02774517.
Twenty five curatively operated patients with carcinoma of the gallbladder were studied to determine the early stage of this cancer according to the depth of invasion. Patients with cancer invasion limited to the proper muscle layer, should be designated as cases with early cancer of the gallbladder and in these cases, metastasis or further invasion was rare and a good postoperative survival rate was obtained. However, if the early cancer was of the nodular or infiltrative type macroscopically, and of tubular adenocarcinoma or adenosquamous carcinoma histologically, the chances of long-term postoperative survival were poor. Based upon our results, it is suggested that extended cholecystectomy should be performed even in patients with early gallbladder cancer.
对25例接受根治性手术的胆囊癌患者进行了研究，以根据浸润深度确定该癌症的早期阶段。癌症浸润仅限于固有肌层的患者，应被指定为胆囊早期癌病例，在这些病例中，转移或进一步浸润很少见，术后生存率良好。然而，如果早期癌症在宏观上是结节型或浸润型，在组织学上是管状腺癌或腺鳞癌，则术后长期生存的机会很差。根据我们的结果，建议即使是早期胆囊癌患者也应进行扩大胆囊切除术。
