乙胺丁醇对耻垢分枝杆菌磷脂代谢的影响。
Effects of ethambutol on phospholipid metabolism in Mycobacterium smegmatis.
作者信息
Kilburn J O, Takayama K, Armstrong E L, Greenberg J
出版信息
Antimicrob Agents Chemother. 1981 Feb;19(2):346-8. doi: 10.1128/AAC.19.2.346.
Abstract
Soon after Mycobacterium smegmatis was exposed to ethambutol, the synthesis of cardiolipin and phosphatidylinositol dimannoside declined. The synthesis of phosphatidylethanolamine continued, but the drug caused this phospholipid to leak out of the cells.
摘要
耻垢分枝杆菌暴露于乙胺丁醇后不久，心磷脂和磷脂酰肌醇二甘露糖苷的合成减少。磷脂酰乙醇胺的合成仍在继续，但该药物导致这种磷脂从细胞中泄漏出来。
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