Demigné C, Rémésy C, Rayssiguier Y
Reprod Nutr Dev (1980). 1980;20(4B):1351-9. doi: 10.1051/rnd:19800726.
The effects of poorly digested carbohydrates in the small intestine on caecal digestion and absorption have been studied in the rat. Even in diets lacking these carbohydrates, there was a noticeable production of volatile fatty acids (VFA) in the caecum. Except for cellulose, the carbohydrates (bran, pectin, guar-gum, crude potato-starch, lactose, lactulose) favoured considerable development of the caecum and enhanced the quantities of VFA present there. On reaching the caecum, they increased ammonia absorption as a result of a higher uptake of blood urea, even if a greater part of the urea nitrogen was used in bacterial protein synthesis. Arteriovenous differences in the caecum showed a considerable absorption of various electrolytes. VFA absorption seemed to be accompanied by a release of Cl- into the caecal contents and by absorption of the main cations, Na+ being absorbed along an unfavourable gradient between the plasma and the caecal contents.
在大鼠身上研究了小肠中消化不佳的碳水化合物对盲肠消化和吸收的影响。即使在缺乏这些碳水化合物的饮食中，盲肠中也有明显的挥发性脂肪酸（VFA）产生。除纤维素外，碳水化合物（麸皮、果胶、瓜尔豆胶、粗马铃薯淀粉、乳糖、乳果糖）有利于盲肠的显著发育，并增加了盲肠中VFA的量。到达盲肠后，由于对血尿素的摄取增加，它们增加了氨的吸收，即使大部分尿素氮用于细菌蛋白质合成。盲肠的动静脉差异显示出各种电解质的大量吸收。VFA的吸收似乎伴随着Cl-释放到盲肠内容物中以及主要阳离子的吸收，Na+是沿着血浆和盲肠内容物之间不利的梯度被吸收的。
