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淋巴细胞上的一种“自身”受体。

A receptor for 'self' on lymphocytes.

作者信息

Kolb H

出版信息

Immunology. 1977 Dec;33(6):859-63.

PMID:73501
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1445547/
Abstract

A large population of lymphocytes is able to form rosettes with syngeneic, allogeneic or closely related xenogeneic erythrocytes. Similar results were found with spleen cells from mice, rats and rabbits. The highest numbers were found in mice where up to 30% of lymphocytes bound autologous erythrocytes. Rosette formation is probably due to stereospecific cell surface receptors since erythrocytes of distant xenogeneic origin were not recognized. Rosette forming cells do not seem to be restricted to the B-cell or T-cell compartment since mouse thymus cells as well as spleen cells from congenitally athymic (nude) mice bound erythrocytes to a similar degree.

摘要

大量淋巴细胞能够与同基因、异基因或亲缘关系密切的异种红细胞形成玫瑰花结。在小鼠、大鼠和兔子的脾细胞中也发现了类似结果。在小鼠中发现的数量最多，高达30%的淋巴细胞能结合自体红细胞。玫瑰花结的形成可能是由于立体特异性细胞表面受体，因为远源异种来源的红细胞未被识别。形成玫瑰花结的细胞似乎并不局限于B细胞或T细胞区室，因为小鼠胸腺细胞以及先天性无胸腺（裸）小鼠的脾细胞结合红细胞的程度相似。

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A receptor for 'self' on lymphocytes.淋巴细胞上的一种“自身”受体。
Immunology. 1977 Dec;33(6):859-63.
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引用本文的文献

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Anti-self receptors. V. Properties of a mouse serum factor that blocks autorosetting receptors on lymphocytes.抗自身受体。V. 一种阻断淋巴细胞自身凝集受体的小鼠血清因子的特性。
Immunology. 1982 Feb;45(2):207-16.
2
Anti-self receptors. IV. H-2-restricted receptors on thymocytes recognize carbohydrate structures on target cells.抗自身受体。IV. 胸腺细胞上的H-2限制性受体识别靶细胞上的碳水化合物结构。
Immunogenetics. 1981 Mar 1;12(5-6):587-99. doi: 10.1007/BF01561699.
3
Anti-self receptors. I. Direct detection of H-2L region-restricted receptors on murine thymocytes.抗自身受体。I. 小鼠胸腺细胞上H-2L区域限制性受体的直接检测。
J Exp Med. 1980 Mar 1;151(3):553-65. doi: 10.1084/jem.151.3.553.
4
Inhibition of phytohaemagglutinin-induced autorosette formation of human peripheral blood lymphocytes by RNA or protein synthesis inhibitor.RNA或蛋白质合成抑制剂对植物血凝素诱导的人外周血淋巴细胞自身花环形成的抑制作用。
Clin Exp Immunol. 1983 Jul;53(1):140-4.

本文引用的文献

1
EFFECT OF GLYCOSIDASES ON THE FATE OF TRANSFUSED LYMPHOCYTES.糖苷酶对输注淋巴细胞命运的影响。
Proc Natl Acad Sci U S A. 1964 Sep;52(3):750-5. doi: 10.1073/pnas.52.3.750.
2
The recirculation of lymphocytes from blood to lymph in the rat.大鼠体内淋巴细胞从血液到淋巴的再循环。
J Physiol. 1959 Apr 23;146(1):54-69. doi: 10.1113/jphysiol.1959.sp006177.
3
Rosette-formation between human lymphocytes and sheep red cells not involving immunoglobulin receptors.人淋巴细胞与绵羊红细胞之间不涉及免疫球蛋白受体的玫瑰花结形成。
Int Arch Allergy Appl Immunol. 1970;39(5-6):658-63. doi: 10.1159/000230390.
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Rosette formation by peripheral lymphocytes.外周淋巴细胞形成玫瑰花结。
Clin Exp Immunol. 1970 May;6(5):681-8.
5
Binding of sheep red blood cells to a large population of human lymphocytes.绵羊红细胞与大量人类淋巴细胞的结合。
Nature. 1971 Apr 23;230(5295):531-2. doi: 10.1038/230531a0.
6
Autologous macrophage-thymocyte interactions.
J Allergy. 1970 Sep;46(3):190-4. doi: 10.1016/0021-8707(70)90097-3.
7
Rosette formation by a mouse fibroblast cell line.小鼠成纤维细胞系形成玫瑰花结。
Nature. 1974 Apr 5;248(448):514-5. doi: 10.1038/248514a0.
8
Macrophage-lymphocyte interaction. I. Characteristics of the antigen-independent-binding of guinea pig thymocytes and lymphocytes to syngeneic macrophages.巨噬细胞-淋巴细胞相互作用。I. 豚鼠胸腺细胞和淋巴细胞与同基因巨噬细胞的抗原非依赖性结合特性。
J Exp Med. 1973 Oct 1;138(4):900-24. doi: 10.1084/jem.138.4.900.
9
Effect of normal mouse serum on mouse lymphocyte transformation in vitro.正常小鼠血清对体外小鼠淋巴细胞转化的影响。
Eur J Immunol. 1974 Feb;4(2):79-86. doi: 10.1002/eji.1830040205.
10
Rosetting of human red blood cells to thymocytes and thymus-derived cells.人红细胞与胸腺细胞及胸腺衍生细胞的玫瑰花结形成。
Clin Exp Immunol. 1973 Nov;15(3):385-92.

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