Blake P A, Allegra D T, Snyder J D, Barrett T J, McFarland L, Caraway C T, Feeley J C, Craig J P, Lee J V, Puhr N D, Feldman R A
N Engl J Med. 1980 Feb 7;302(6):305-9. doi: 10.1056/NEJM198002073020601.
In September and October 1978, after a case of cholera had been discovered in southwestern Louisiana, 10 more Vibrio cholerae O-Group 1 infections were detected in four additional clusters. All 11 infected persons had recently eaten cooked crabs from five widely separated sites in the coastal marsh, and a matched-triplet case-control study showed a significant relation between cholera and eating such crabs (P = 0.007). V. cholerae O1 was isolated from estuarine water, from fresh shrimp, from a leftover cooked crab from a patient's refrigerator, and from sewage in six towns, including three without identified cases. All isolates in Louisiana and an isolate from a single unexplained case in Texas in 1973 were biotype El Tor and serotype inaba; they were hemolytic and of a phage type unique to the United States--suggesting that the organism persisted undetected along the Gulf Coast for at least five years.
1978年9月和10月，路易斯安那州西南部发现一例霍乱病例后，在另外四个聚集性病例中又检测到10例O1群霍乱弧菌感染。所有11名感染者近期都食用了来自沿海沼泽五个相距甚远地点的熟蟹，一项配对三胞胎病例对照研究表明，霍乱与食用此类螃蟹之间存在显著关联（P = 0.007）。从河口水中、鲜虾、患者冰箱里剩下的一只熟蟹以及六个城镇的污水中分离出了O1群霍乱弧菌，其中三个城镇未发现确诊病例。路易斯安那州的所有分离株以及1973年得克萨斯州一例不明原因病例的分离株均为埃尔托生物型和稻叶血清型；它们具有溶血特性，且属于美国特有的噬菌体类型，这表明该病原体在墨西哥湾沿岸至少潜伏了五年未被发现。
