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1976 - 1977年得克萨斯州休斯顿乙型流感病毒感染的流行病学观察

Epidemiologic observations of influenza B virus infections in Houston, Texas, 1976-1977.

作者信息

Glezen W P, Couch R B, Taber L H, Paredes A, Allison J E, Frank A L, Aldridge C

出版信息

Am J Epidemiol. 1980 Jan;111(1):13-22. doi: 10.1093/oxfordjournals.aje.a112865.

Abstract

Influenza B virus infections were documented in Houston, Texas, in 726 patients with febrile respiratory illnesses who presented to representative primary care facilities during the 1976-1977 respiratory disease season. This epidemic followed a "herald wave" of illness associated with influenza B during the preceding spring. Over one-half the virus isolates were from children aged 5-19 years, and school absenteeism rates indicated that about 40 per cent of the students in the Houston area were ill enough to miss school during the epidemic. The rapid rise in the number of cases among students after the school holiday recess demonstrated the importance of school attendance for the rapid dissemination of influenza viruses. During the later phase of the epidemic, most of the cases were preschool children and adults. In addition to disease of the respiratory tract, the epidemic was accompanied by cases of Reye's syndrome at a rate expected for an urban area.

摘要

1976 - 1977年呼吸道疾病流行季节期间,在得克萨斯州休斯敦,726名出现发热性呼吸道疾病的患者被记录感染了乙型流感病毒,这些患者前往了有代表性的初级保健机构。此次疫情之前的春季曾出现过与乙型流感相关的“先兆性发病潮”。超过一半的病毒分离株来自5至19岁的儿童,学校缺勤率表明,在疫情期间,休斯敦地区约40%的学生因病严重到无法上学。学校假期结束后学生中病例数迅速上升,这表明上学对于流感病毒的快速传播具有重要作用。在疫情后期,大多数病例是学龄前儿童和成年人。除呼吸道疾病外,该疫情还伴有按城市地区预期发生率出现的瑞氏综合征病例。

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