Griffith J L, Davis J T
J Thorac Cardiovasc Surg. 1980 Mar;79(3):447-52.
Twenty years of experience with operative treatment of carcinoma of the esophagus and cardia are reviewed. Of the 513 patients with biopsy-proved malignancy reviewed, 211 (41%) underwent gastroesophagectomy. The hospital mortality rate for the patients operated upon was 12%. The 3 year survival rate was 26% and the 5 year survival rate was 15% for the entire surgical series. Squamous cell carcinomas of the lower third were the most favorable subgroup (25% 5 year survival) and lower third adenocarcinomas the least favorable (8% 5 year survival). Our procedure of choice is a one-stage resection with stomach used to restore continuity. Operative details and perioperative management are reviewed. The single-layer wire technique of anastomosis seems to give acceptably low rates of anastomotic leak (4.2%) and stricture (2.3%). Preoperative radiation was not used in this series.
回顾了20年食管和贲门癌手术治疗的经验。在513例经活检证实为恶性肿瘤的患者中，211例（41%）接受了胃食管切除术。接受手术患者的医院死亡率为12%。整个手术系列的3年生存率为26%，5年生存率为15%。下三分之一的鳞状细胞癌是最有利的亚组（5年生存率为25%），而下三分之一的腺癌是最不利的（5年生存率为8%）。我们选择的手术方法是一期切除，用胃恢复连续性。回顾了手术细节和围手术期管理。单层丝线吻合技术似乎能使吻合口漏（4.2%）和狭窄（2.3%）的发生率低至可接受的水平。本系列未采用术前放疗。
