Griffith J L, Davis J T
J Thorac Cardiovasc Surg. 1980 Mar;79(3):447-52.
Twenty years of experience with operative treatment of carcinoma of the esophagus and cardia are reviewed. Of the 513 patients with biopsy-proved malignancy reviewed, 211 (41%) underwent gastroesophagectomy. The hospital mortality rate for the patients operated upon was 12%. The 3 year survival rate was 26% and the 5 year survival rate was 15% for the entire surgical series. Squamous cell carcinomas of the lower third were the most favorable subgroup (25% 5 year survival) and lower third adenocarcinomas the least favorable (8% 5 year survival). Our procedure of choice is a one-stage resection with stomach used to restore continuity. Operative details and perioperative management are reviewed. The single-layer wire technique of anastomosis seems to give acceptably low rates of anastomotic leak (4.2%) and stricture (2.3%). Preoperative radiation was not used in this series.
回顾了20年食管和贲门癌手术治疗的经验。在513例经活检证实为恶性肿瘤的患者中,211例(41%)接受了胃食管切除术。接受手术患者的医院死亡率为12%。整个手术系列的3年生存率为26%,5年生存率为15%。下三分之一的鳞状细胞癌是最有利的亚组(5年生存率为25%),而下三分之一的腺癌是最不利的(5年生存率为8%)。我们选择的手术方法是一期切除,用胃恢复连续性。回顾了手术细节和围手术期管理。单层丝线吻合技术似乎能使吻合口漏(4.2%)和狭窄(2.3%)的发生率低至可接受的水平。本系列未采用术前放疗。