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猫和狗肾上腺中肾上腺素和去甲肾上腺素的反射性释放。

The reflex release of adrenaline and noradrenaline from the adrenal glands of cats and dogs.

作者信息

Critchley J A, Ellis P, Ungar A

出版信息

J Physiol. 1980 Jan;298:71-8. doi: 10.1113/jphysiol.1980.sp013067.

DOI:10.1113/jphysiol.1980.sp013067
PMID:7359443
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1279102/
Abstract
  1. We have studied the release of noradrenaline and adrenaline from the adrenal glands of dogs and cats in response to the lowering of carotid sinus pressure (baroreceptor tests) and to the perfusion of the vascularly isolated carotid bifurcations with hypoxic blood (chemoreceptor tests). 2. In cats, the resting output of catecholamines had a ratio of noradrenaline to adrenaline of 1:1. The ratio in the incremental release during baroreceptor tests rose to 3:1, and during chemoreceptor tests it fell to 1:6. 3. In dogs, the ratio of noradrenaline to adrenaline at rest was 1:4. The ratio did not change over a wide range of outputs during baroreceptor tests, chemoreceptor tests and splanchnic nerve stimulation. 4. The release of catecholamines in response to baroreceptor tests in the cat was abolished by hexamethomium bromide at doses that did not diminish the response to chemoreceptor tests.
摘要
  1. 我们研究了犬和猫的肾上腺在应对颈动脉窦压力降低(压力感受器试验)以及用缺氧血液灌注血管分离的颈动脉分叉处(化学感受器试验)时去甲肾上腺素和肾上腺素的释放情况。2. 在猫中,儿茶酚胺的静息输出量中去甲肾上腺素与肾上腺素的比例为1:1。在压力感受器试验期间,增量释放中的比例升至3:1,而在化学感受器试验期间则降至1:6。3. 在犬中,静息时去甲肾上腺素与肾上腺素的比例为1:4。在压力感受器试验、化学感受器试验和内脏神经刺激期间,在广泛的输出范围内该比例没有变化。4. 在猫中,六甲溴铵在不减弱对化学感受器试验反应的剂量下可消除对压力感受器试验的儿茶酚胺释放反应。

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The reflex release of adrenaline and noradrenaline from the adrenal glands of cats and dogs.猫和狗肾上腺中肾上腺素和去甲肾上腺素的反射性释放。
J Physiol. 1980 Jan;298:71-8. doi: 10.1113/jphysiol.1980.sp013067.
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本文引用的文献

1
Pressor responses to electrical stimulation of the carotid sinus nerve in cats.猫对颈动脉窦神经电刺激的升压反应。
J Physiol. 1949 Sep;109(3-4):259-71. doi: 10.1113/jphysiol.1949.sp004390.
2
Liberation of nor-adrenaline and adrenaline from the suprarenals of the cat during carotid occlusion.猫颈动脉闭塞期间肾上腺中去甲肾上腺素和肾上腺素的释放。
Am J Physiol. 1951 Aug;166(2):284-8. doi: 10.1152/ajplegacy.1951.166.2.284.
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ACTIVITY OF THE ADRENAL MEDULLA AND ITS REGULATION.肾上腺髓质的活动及其调节
Physiol Rev. 1964 Apr;44:186-218. doi: 10.1152/physrev.1964.44.2.186.
4
Selective activation of noradrenaline and adrenaline producing cells in the cat's adrenal gland by hypothalamic stimulation.通过下丘脑刺激选择性激活猫肾上腺中产生去甲肾上腺素和肾上腺素的细胞。
Circ Res. 1954 May;2(3):191-5. doi: 10.1161/01.res.2.3.191.
5
[Effect of various afferent nerves stimuli on the composition of incretion of adrenal medulla in cat].[不同传入神经刺激对猫肾上腺髓质分泌成分的影响]
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1953;219(3):242-7.
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[Adrenalin and noradrenalin in adrenal blood in the dog during asphyxia].[窒息期间犬肾上腺血液中的肾上腺素和去甲肾上腺素]
Rev Soc Argent Biol. 1952 Apr-May;28(1-2):7-11.
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Preferential release of adrenaline from the adrenal medulla by muscarine and pilocarpine.毒蕈碱和毛果芸香碱促使肾上腺素从肾上腺髓质优先释放。
Nature. 1965 Dec 11;208(5015):1102-3. doi: 10.1038/2081102a0.
8
Preferential secretion of adrenaline or noradrenaline by the cat adrenal in vivo in response to different stimuli.猫肾上腺在体内对不同刺激的肾上腺素或去甲肾上腺素的优先分泌。
Br J Pharmacol. 1971 Dec;43(4):764-75. doi: 10.1111/j.1476-5381.1971.tb07212.x.
9
Proceedings: The release of adrenaline and noradrenaline by the adrenal glands of cats and dogs in reflexes arising from the carotid chemoreceptors and baroreceptors.论文:猫和狗的肾上腺在由颈动脉化学感受器和压力感受器引发的反射中释放肾上腺素和去甲肾上腺素的情况。
J Physiol. 1973 Oct;234(2):111P-112P.
10
Impaired secretion of epinephrine in response to insulin among hypophysectomized dogs.垂体切除的狗对胰岛素反应时肾上腺素分泌受损。
Proc Natl Acad Sci U S A. 1968 Oct;61(2):522-8. doi: 10.1073/pnas.61.2.522.