猫和狗肾上腺中肾上腺素和去甲肾上腺素的反射性释放。
The reflex release of adrenaline and noradrenaline from the adrenal glands of cats and dogs.
作者信息
Critchley J A, Ellis P, Ungar A
出版信息
J Physiol. 1980 Jan;298:71-8. doi: 10.1113/jphysiol.1980.sp013067.
Abstract
- We have studied the release of noradrenaline and adrenaline from the adrenal glands of dogs and cats in response to the lowering of carotid sinus pressure (baroreceptor tests) and to the perfusion of the vascularly isolated carotid bifurcations with hypoxic blood (chemoreceptor tests). 2. In cats, the resting output of catecholamines had a ratio of noradrenaline to adrenaline of 1:1. The ratio in the incremental release during baroreceptor tests rose to 3:1, and during chemoreceptor tests it fell to 1:6. 3. In dogs, the ratio of noradrenaline to adrenaline at rest was 1:4. The ratio did not change over a wide range of outputs during baroreceptor tests, chemoreceptor tests and splanchnic nerve stimulation. 4. The release of catecholamines in response to baroreceptor tests in the cat was abolished by hexamethomium bromide at doses that did not diminish the response to chemoreceptor tests.
摘要
- 我们研究了犬和猫的肾上腺在应对颈动脉窦压力降低（压力感受器试验）以及用缺氧血液灌注血管分离的颈动脉分叉处（化学感受器试验）时去甲肾上腺素和肾上腺素的释放情况。2. 在猫中，儿茶酚胺的静息输出量中去甲肾上腺素与肾上腺素的比例为1:1。在压力感受器试验期间，增量释放中的比例升至3:1，而在化学感受器试验期间则降至1:6。3. 在犬中，静息时去甲肾上腺素与肾上腺素的比例为1:4。在压力感受器试验、化学感受器试验和内脏神经刺激期间，在广泛的输出范围内该比例没有变化。4. 在猫中，六甲溴铵在不减弱对化学感受器试验反应的剂量下可消除对压力感受器试验的儿茶酚胺释放反应。
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